HsaEX0070246 @ hg19
Exon Skipping
Gene
ENSG00000141968 | VAV1
Description
vav 1 guanine nucleotide exchange factor [Source:HGNC Symbol;Acc:12657]
Coordinates
chr19:6836443-6843177:+
Coord C1 exon
chr19:6836443-6836579
Coord A exon
chr19:6836996-6837061
Coord C2 exon
chr19:6843146-6843177
Length
66 bp
Sequences
Splice sites
3' ss Seq
TTTGTCTCCTGGGTGTTTAGGGC
3' ss Score
7.46
5' ss Seq
CATGTGAGT
5' ss Score
7.83
Exon sequences
Seq C1 exon
GTCTGCCCAAGATGGAGGTGTTTCAGGAATACTACGGGCTTCCTCCACCCCCTGGAGCCATTGGACCCTTTCTACGGCTCAACCCTGGAGACATTGTGGAGCTCACGAAGGCTGAGGCTGAACAGAACTGGTGGGAG
Seq A exon
GGCAGAAATACATCTACTAATGAAATTGGCTGGTTTCCTTGTAACAGGGTGAAGCCCTATGTCCAT
Seq C2 exon
GGCCCTCCTCAGGACCTGTCTGTTCATCTCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000141968_CASSETTE3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.043 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0765312=SH3_2=PU(88.9=87.0)
A:
PF0001823=SH3_1=PD(34.2=59.1)
C2:
PF0765312=SH3_2=PD(6.7=27.3),PF0001719=SH2=PU(0.1=0.0)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTGCCCAAGATGGAGGTGTT
R:
AGAGATGAACAGACAGGTCCTGA
Band lengths:
167-233
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)