HsaEX0073258 @ hg19
Exon Skipping
Gene
ENSG00000198169 | ZNF251
Description
zinc finger protein 251 [Source:HGNC Symbol;Acc:13045]
Coordinates
chr8:145979577-145980970:-
Coord C1 exon
chr8:145980790-145980970
Coord A exon
chr8:145980081-145980188
Coord C2 exon
chr8:145979577-145979706
Length
108 bp
Sequences
Splice sites
3' ss Seq
CTGAGTTCTCCCCACTGAAGGTA
3' ss Score
5.58
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
AGGCCCCGCAGGGGGCGGGGAAGCCTGCGTGTGCGCAGCTCGGCCCGGCCCGCCCTCTTCATCCTAGCCCGCCCCCTCCCCGGCTCTGGACCCGGTTCTGTGGGAGGGTCCGTTCCGGGCTCGGTGCGACTGCGCAGCTCCTCGGCGCTTCCTCGGTGGCTTCCCCGGGTCGAGCAAACAG
Seq A exon
GTAAGTTCGGGGAGACTTCAGGCCAGGGCAGTCTCCTGTCTTCTCTTGGAAACCACAGCAGCCCATGCACACAGAATGGCAGCCACATTCCAGCTTCCAGGGCACCAG
Seq C2 exon
GAGATGCCGCTGACCTTCCAGGATGTGGCCGTGTACTTCTCTCAGGCGGAGGGGCGGCAGCTGGGCCCCCAGCAGCGGGCGCTCTACCGGGATGTGATGCTGGAGAACTATGGGAACGTGGCCTCTCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198169_MULTIEX1-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref, Alt. ATG (>10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0135222=KRAB=PU(95.1=88.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCGCCCTCTTCATCCTAG
R:
GTTCTCCAGCATCACATCCCG
Band lengths:
242-350
Functional annotations
There are 1 annotated functions for this event
PMID: 32249828
This event
[CRISPR screen]. This alternative exon is implicated in cell fitness by a CRISPR-based exon deletion phenotypic screen in RPE-1 cells.
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)