HsaEX1003666 @ hg38
Exon Skipping
Gene
ENSG00000151150 | ANK3
Description
ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]
Coordinates
chr10:60067935-60084830:-
Coord C1 exon
chr10:60084602-60084830
Coord A exon
chr10:60068637-60068869
Coord C2 exon
chr10:60067935-60068009
Length
233 bp
Sequences
Splice sites
3' ss Seq
GAATATTTTAAGGGAATTAGTGG
3' ss Score
-8.76
5' ss Seq
CTGGTGAGA
5' ss Score
7.54
Exon sequences
Seq C1 exon
ATTTTGGCTTGCAGACTGCCATCAAGTTTTAGAAACTGTGGGGTTAGCCACGCAACTGTACAGAGAATTGATATGTGTTCCATATATGGCCAAGTTTGTTGTTTTTGCCAAAATGAATGATCCCGTAGAATCTTCCTTGCGATGTTTCTGCATGACAGATGACAAAGTGGACAAAACTTTAGAGCAACAAGAGAATTTTGAGGAAGTCGCAAGAAGCAAAGATATTGAG
Seq A exon
TGGTGAGACCTTAAAGCTTGTGGACCGCCTCTCTGAAGAAGAAAAAAAGATGCAGTCCGAGTTGTCCGATGAGGAAGAAAGTACCTCAAGAAACACGTCGTTGTCCGAGACTTCCCGGGGTGGCCAGCCTTCGGTTACAACGAAGTCTGCTAGAGATAAGAAAACAGAGGCAGCACCTTTAAAATCAAAGAGTGAAAAGGCCGGCAGTGAGAAAAGGAGCAGTAGAAGGACTG
Seq C2 exon
GTCCACAGAGTCCATGTGAACGGACAGATATCAGGATGGCAATAGTAGCCGATCACCTGGGACTTAGTTGGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000151150_MULTIEX2-17/27=11-18
Average complexity
C3*
Mappability confidence:
95%=95=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.712 C2=0.180
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0053117=Death=PU(19.0=61.5)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATTTTGGCTTGCAGACTGCCA
R:
GTCCCAGGTGATCGGCTACTA
Band lengths:
292-525
Functional annotations
There are 1 annotated functions for this event
PMID: 9312002
This event
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001681; ELM sequence: FPPPP; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains