HsaEX1016898 @ hg38
Exon Skipping
Gene
ENSG00000232629 | HLA-DQB2
Description
major histocompatibility complex, class II, DQ beta 2 [Source:HGNC Symbol;Acc:HGNC:4945]
Coordinates
chr6:32756098-32757883:-
Coord C1 exon
chr6:32757773-32757883
Coord A exon
chr6:32757281-32757304
Coord C2 exon
chr6:32756098-32756466
Length
24 bp
Sequences
Splice sites
3' ss Seq
TGTATAACTTCCTTTTGTAGGAC
3' ss Score
9.98
5' ss Seq
CAGGTAATA
5' ss Score
8.55
Exon sequences
Seq C1 exon
GGGCTCAGTCTGAATCTGCCCAGAGCAAGATGCTGAGTGGCATTGGAGGCTTCGTGCTGGGGCTGATCTTCCTCGGGCTGGGCCTTATCATCCGTCACAGGGGTCAGAAAG
Seq A exon
GACCTCGAGGGCCTCCACCAGCAG
Seq C2 exon
GACTCCTGCACTGACTCCTGAGGACTTTTGTCTGGGATTGGTCATCACTCTTCTGTAATGCCCACCTGCCCCTGCCCAGAATTCCTAGCTGCCTGTGTCACCCTGTCCCACTGAGGTCAGAGTCCTACAGTGGCTCATGCAGCCACAGGTCACCTTCTGTGATCCCCATCCCAAGGCACTGGTGGTGACTCTGCTTCCTGCACTGACCCAGAGCCTCTGCCTGTGCACTGCAAGCTGTGTCTACTCAGGCCCCAAGGGGCATCTCTGTTTCCATTCTCCCCCCACAGACCTGTCAAGAGAAGCATGACAAACAAAATCATTTACCTGACTTTAGTGCTTTTTCCCATAATTAAACCTGATTCTGAGTTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000232629-'6-11,'6-10,7-11
Average complexity
C2
Mappability confidence:
100%=75=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.053 A=0.597 C2=0.784
Domain overlap (PFAM):
C1:
PF0765410=C1-set=PD(9.3=23.7)
A:
NO
C2:
NO
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCCGTCACAGGGGTCAGAAA
R:
GCAGCTAGGAATTCTGGGCAG
Band lengths:
114-138
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains