HsaEX1017999 @ hg38
Exon Skipping
Gene
ENSG00000091409 | ITGA6
Description
integrin subunit alpha 6 [Source:HGNC Symbol;Acc:HGNC:6142]
Coordinates
chr2:172489485-172491122:+
Coord C1 exon
chr2:172489485-172489658
Coord A exon
chr2:172490212-172490389
Coord C2 exon
chr2:172491024-172491122
Length
178 bp
Sequences
Splice sites
3' ss Seq
TTATCCTCACCATTTCACAGATG
3' ss Score
8.41
5' ss Seq
AAGGTTTGC
5' ss Score
5.42
Exon sequences
Seq C1 exon
GTAATAAACTTAGGTAAACCTCTTACAAACCTCGGCACAGCAACCTTGAACATTCAGTGGCCAAAAGAAATTAGCAATGGGAAATGGTTGCTTTATTTGGTGAAAGTAGAATCCAAAGGATTGGAAAAGGTAACTTGTGAGCCACAAAAGGAGATAAACTCCCTGAACCTAACG
Seq A exon
ATGAGGACATTAAGATTCAGAGAGCAAGTAACTCTCTCAGTCACTCAGGCGTTAAGAGACAGATTCCACATACAAGCCCTGCTCTGCCTGATGTCAAAGCCTGTACTGTTAACCCCTCTCTCTATACTGCTCCATGCTTAGATAACTGGCCTATCATTTGTGTTCCAGTTTGATGAAG
Seq C2 exon
GAGTCTCACAACTCAAGAAAGAAACGGGAAATTACTGAAAAACAGATAGATGATAACAGAAAATTTTCTTTATTTGCTGAAAGAAAATACCAGACTCTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091409_MULTIEX2-2/2=1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.030 A=0.000 C2=0.208
Domain overlap (PFAM):
C1:
PF084417=Integrin_alpha2=FE(12.0=100)
A:
PF084417=Integrin_alpha2=PD(5.5=53.2)
C2:
PF084417=Integrin_alpha2=PD(6.2=12.1)
Main Inclusion Isoform:
ENST00000442250fB17763
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTTACAAACCTCGGCACAGC
R:
AGAGTCTGGTATTTTCTTTCAGCA
Band lengths:
252-430
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains