HsaEX1025234 @ hg38
Exon Skipping
Gene
ENSG00000130287 | NCAN
Description
neurocan [Source:HGNC Symbol;Acc:HGNC:2465]
Coordinates
chr19:19240603-19245457:+
Coord C1 exon
chr19:19240603-19240685
Coord A exon
chr19:19242734-19242903
Coord C2 exon
chr19:19245313-19245457
Length
170 bp
Sequences
Splice sites
3' ss Seq
TTGTACATGAATGTTCACAGCCC
3' ss Score
4.04
5' ss Seq
AAGGTGGGT
5' ss Score
8.23
Exon sequences
Seq C1 exon
GCTTTGGGCATGAAAACACGTGGATCGGCCTGAACGACAGGATCGTGGAGAGAGATTTCCAGTGGACGGACAACACCGGGCTG
Seq A exon
CCCCACTATTCACAATAGCCAAGGTGGGAACATCCAAAATACCCATCAACAGATGAAGGAAGAGACAAAATGTGGTCCATCCATGCAATGGAATATTGTTCGGCCATAAAGGAGAAGTTGGCCAGGTGCAGTGGTTCATGCCTGCAATCCCAGCACTTTTGGAGGCCAAG
Seq C2 exon
CAATTTGAGAACTGGCGAGAGAACCAGCCGGACAATTTCTTCGCGGGTGGCGAGGACTGTGTGGTGATGGTGGCGCATGAAAGCGGGCGCTGGAACGATGTCCCCTGCAACTACAACCTACCCTATGTCTGCAAGAAGGGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130287-'24-32,'24-31,25-32
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.200 C2=0.000
Domain overlap (PFAM):
C1:
PF0253517=Zip=FE(17.2=100),PF0005916=Lectin_C=FE(25.5=100)
A:
PF0005916=Lectin_C=PD(4.7=50.0)
C2:
PF0253517=Zip=FE(30.6=100),PF0005916=Lectin_C=PD(43.4=93.9)
Main Inclusion Isoform:
ENST00000252575fB20818
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTTTGGGCATGAAAACACGT
R:
CTGTGCCCTTCTTGCAGACAT
Band lengths:
228-398
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains