HsaEX1027499 @ hg38
Exon Skipping
Gene
ENSG00000138735 | PDE5A
Description
phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784]
Coordinates
chr4:119538960-119542634:-
Coord C1 exon
chr4:119542459-119542634
Coord A exon
chr4:119541754-119542196
Coord C2 exon
chr4:119538960-119539019
Length
443 bp
Sequences
Splice sites
3' ss Seq
TGCCTTTGCTTTTTCTGCAGAAA
3' ss Score
10.26
5' ss Seq
AGGGTCAGT
5' ss Score
5.85
Exon sequences
Seq C1 exon
GGGTTTGCCAACTTGTTAATAAGATGGAGGAGAATACTGGCAAGGTTAAGCCTTTCAACCGAAATGACGAACAGTTTCTGGAAGCTTTTGTCATCTTTTGTGGCTTGGGGATCCAGAACACGCAGATGTATGAAGCAGTGGAGAGAGCCATGGCCAAGCAAATGGTCACATTGGAG
Seq A exon
AAAGCAATATTGACTTTAATAATCCATTGACACAGATGACTACTGCCAATTATCTGTCTCTTTCCCATTGCCTGAGCCTCCCCATCTTTCCGTGAGAACAGTTGTGGAAAAAAATTAAAAATAAACAAACAAACAAAAAACAGAAACCCTAGGCACTCTTAAGAGAATTAGAAGTGAGGAAAAGAAAAAATAAAATCAACGAAAAGCAGGAAGAGTTTTAACTCCTGGAATCATCTGAGAAACTATTTCAAACTATAAATTTATATACCCTACTTCTGAAAGTTCTGATTCAGCAAGTCTTGGGTAGAAGCTGGGAATCTGTATGACTACCAAGCTCCCCCAGGTGACTCTGAATGTGCAGGTAGCGAGTGAAGAAACCACTGGCTCCCAGGGACTGACCGAGGAACACTCTTTCTCACAAAGGACCAGCCGACTCCAACAGG
Seq C2 exon
GTTCTGTCGTATCATGCTTCAGCAGCAGAGGAAGAAACAAGAGAGCTACAGTCGTTAGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138735_CASSETTE4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.085 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0159021=GAF=PD(23.4=62.7)
A:
NO
C2:
NO
Main Inclusion Isoform:
ENST00000264805fB22224
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGTTTGCCAACTTGTTAATAAGA
R:
CGCTAACGACTGTAGCTCTCT
Band lengths:
236-679
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains