HsaINT0122122 @ hg38
Intron Retention
Gene
ENSG00000138735 | PDE5A
Description
phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784]
Coordinates
chr4:119538960-119542634:-
Coord C1 exon
chr4:119542459-119542634
Coord A exon
chr4:119539020-119542458
Coord C2 exon
chr4:119538960-119539019
Length
3439 bp
Sequences
Splice sites
5' ss Seq
GAGGTGGGT
5' ss Score
7.07
3' ss Seq
CTTCTTTTCCTACCCTGTAGGTT
3' ss Score
10.94
Exon sequences
Seq C1 exon
GGGTTTGCCAACTTGTTAATAAGATGGAGGAGAATACTGGCAAGGTTAAGCCTTTCAACCGAAATGACGAACAGTTTCTGGAAGCTTTTGTCATCTTTTGTGGCTTGGGGATCCAGAACACGCAGATGTATGAAGCAGTGGAGAGAGCCATGGCCAAGCAAATGGTCACATTGGAG
Seq A exon
GTGGGTGAAGTTTAGGGACCTCTCACACTGTACAGCCAAACCCTCATCTTTTACCTTTCCCTCATAATCACTCATGGTGTGTGTGTGTTCCGTCATTGTGTCCTCACCAAAATTATGTGATTTAGATGATGAGATCCTTATTGTCCTCAACTAAAGAATGAAAGAAACTAAGACTCAGAATATTTAAGAAACTTGTCAAATGTCATATAACCAAACCACAACTCAGGATGTTTATCCCTTTATGCCTTTGCTTTTTCTGCAGAAAGCAATATTGACTTTAATAATCCATTGACACAGATGACTACTGCCAATTATCTGTCTCTTTCCCATTGCCTGAGCCTCCCCATCTTTCCGTGAGAACAGTTGTGGAAAAAAATTAAAAATAAACAAACAAACAAAAAACAGAAACCCTAGGCACTCTTAAGAGAATTAGAAGTGAGGAAAAGAAAAAATAAAATCAACGAAAAGCAGGAAGAGTTTTAACTCCTGGAATCATCTGAGAAACTATTTCAAACTATAAATTTATATACCCTACTTCTGAAAGTTCTGATTCAGCAAGTCTTGGGTAGAAGCTGGGAATCTGTATGACTACCAAGCTCCCCCAGGTGACTCTGAATGTGCAGGTAGCGAGTGAAGAAACCACTGGCTCCCAGGGACTGACCGAGGAACACTCTTTCTCACAAAGGACCAGCCGACTCCAACAGGGTCAGTCCTTTCTATATATGTTTCACTAACTGCCTTGAAATTATTCAGTTGATGTAACATGGAGATTTCTTATCTAGTTGAAATTAGAGAAAATCAGTGTTTGGGATATAATAACATTTCCCTCAATCTCTCTTAAGTACATAACTAACCTTAAAGAGCTAGAGAGACATATATTATATAAAATATACCAGATGGTACCCTTTACTTTCTATGCTGAATATATTATACTAATAGGTTTGCTACAGTATTATATAAAAGACTTTGAATATATAAACCAGTGGAAATCTGTTTCAAATATATATGTACACATATACACACAAATATATATTTCAAATATAGTTTCAATTAGGTGCATATACACATGTACATATGTGTTCAAATAGCTTTAAATATACAGATACACATATATACATATATCTATATATGTGTTTATTATAAAATATATAAATATAATTTTTAATCTAATTTTTTCAGTTTCATGGTTTTTCATTGAAAAATTTAATCTAAGTCAGCTATCAATTAGAAGTTATTTCTTTTTTAAATGTTTTATTATGGAAAGTTTCAAGCATATACAGAAGTAGACAGAAAGCTTAATAAGCCCTCACATACTCATCATCCATTCAGTAATTATCAACCCATGACCATTATCACTCCATCCATTCCCACCGCACTCCTCTGCACTTCCCTTCCCCTCCCACTGGCTTAGTTTGAAGCAATCCCAGACATTGTATTACTTTGTTCAGAATCTCTGAATATTTTCCTGATTGAGACTTATTTCTATCTTTGTAGCTCTCTTTCAGTTAAATATATGGATAATTAGGCTTTTACCTAGTATAAAAAGTTTTTGATTTCAGGTCATATGTGTAGTCATTTCTATGATCATAGATATAACTTTGAAAAAAATGGTCCTTTCTTTATGAGACCATTGGACAAAAGCCAAGGGCACAAACCCCTCAGGTCTTCAAAAGACAGTGAATTATTTTGACCTGGAAGTTGTGATCATTCTAATAACAATAAAATAATGATGACAATAAAAGTAACTAAATTTATCAGATGTTTCAATTGTATTCTAATGCTTACATGTATTAACAAAGTTAATCCTTATGCCCCATGTGTAAGTTATTTTTATCTTTTGTGTGTGATAAAATTTTTTTAACTTAGAATGTATTGTGTCATTTCTTTATTCATGTATCCATGTTGCACTGCACTTGTTAATATTAGTCTAACTCATGGACACAGTATTAGCTTTTCTTGGGAACCACCACTGTAGTCTCAGTAGCAACAGGTTATAGCCATGACCCATCAATTTCACACGTGCAGGAGAGAGCAGCTGTGAGTTTCTTGAGGTTTCCTAGTGACTAATGGTTCAAATGGCAAGAAAGATGCAATGTAGTGCAGTATGGTAACAGTTCTAAATCATAAGATAGTACAAATATGTATCATTTGGCTTTAAATTTTTAATTACTTAAAATTTTAAAGACTGGTTCAAGAAATACTGGTTTGGGTTGCTGAATTACTTTACTCACCATTTAAAGTTTGAAAATGAGCTACCTTTTCATCAATGCTTTTTAAGCTTTTGGGGTTTTTTTTGTAAATCTGTGTTGTCTCTCTCAAAAATGAACTTTAAAAAAATATGCTTTCAAAGCATGATAGATACTTTAAATACAACCACTACCTTGGTTTAAAAGAATGTTTAAAAAAAATCCCATTGCAGTTTGGGTAACCCTTACATGAAATGCTTGAGACCAGAAGTGTTTTGTATTTTGCATTTTTTTTCAGATTTTTGGAACATGTGCATTATACTTAATGGTTGAGCAGTCCAAATCCAAAAATCTCAAACTCAAAAATGTTTCAAAATCCAAAATTCTCTGAGCAGCAGCATGACACTCAAAAGGAAATGCTCATTAGAGGATTTTGGATTTCAGATTTTTAGGTTTGGGATGCTCAACTTGTAATTAGAAATGATTGCTTTTGAAAATGGAAATTAAGTTAATAAGCCTGATTTTTTAACTCTAAGTAATGGAACGTGTATAGGTTAGGAATTGAAAGCTGGGTCCTAAATCTCCTTGTCCTCTCACTAGGTGTGAGCTTACAGCCAAATCATGTGACTCCCTGAGGCTCAGTGTCCCCAACTGTCAATGGATGGCTTTACAGGCCAGCACTACTCTCTTCTCACCTCTTAAATTGTAGGAGTGTAAAGGGATCCTTAAATCTGCATGACTGTGTCCCAGGCATCCAGTTTTTCTGTGTGAATTCTAGAATGGTTACAGGCCTCATCTGAGAGCCACTTGTAGACTACTTTCTTTCCAAATATTAATATCAAAATGTCAGATTATGCAGAGATTTTCTCTTTAATTCTGTACACAAGCAGAAATAGCTAAAGTCAATATTGTCTTAAAAAAAAAAAACAAAATAAATTTTCTGCCAAAGTTTGAGCCAAAAGTTATTTCTAGGCTGGCTTATAAATAATGTGTTTGTTATAGCAATAATGTCAGACTGGAAGTTACAAGAGTTTTCTTTAAACATAGGGAGTATAACTTTTTGTTTTCCAAAACAAGCAATGGAATCTAAATCTGGGTTTTTCACTGTTGAAGAAAACAGCAAACAAGATTTGGCATTCTGAGGAGTCTAATTATCTCTCCAAGAAGACTTAGCAGAATTCCAAGCTTGAAGTTCTAGTCTACATGTGGTAGTTCTCTCCTGTGTAACCTGGACTTCTTTTCCTACCCTGTAG
Seq C2 exon
GTTCTGTCGTATCATGCTTCAGCAGCAGAGGAAGAAACAAGAGAGCTACAGTCGTTAGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138735:ENST00000354960:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.085 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0159021=GAF=PD(23.4=62.7)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development