HsaEX6000996 @ hg19
Exon Skipping
Gene
ENSG00000011405 | PIK3C2A
Description
phosphoinositide-3-kinase, class 2, alpha polypeptide [Source:HGNC Symbol;Acc:8971]
Coordinates
chr11:17122825-17126852:-
Coord C1 exon
chr11:17126716-17126852
Coord A exon
chr11:17124209-17124378
Coord C2 exon
chr11:17122825-17122981
Length
170 bp
Sequences
Splice sites
3' ss Seq
ATTGTGTATGTTTTTTATAGGCT
3' ss Score
8.1
5' ss Seq
AAGGTATAA
5' ss Score
7.08
Exon sequences
Seq C1 exon
GCATGGTGGAGCTGGTTCCTGCTTCCGATACCCTCAGGAAAATCCAAGTGGAATATGGTGTGACAGGATCCTTTAAAGATAAACCACTTGCAGAGTGGCTAAGGAAATACAATCCCTCTGAAGAAGAATATGAAAAG
Seq A exon
GCTTCAGAGAACTTTATCTATTCCTGTGCTGGATGCTGTGTAGCCACCTATGTTTTAGGCATCTGTGATCGACACAATGACAATATAATGCTTCGAAGCACGGGACACATGTTTCACATTGACTTTGGAAAGTTTTTGGGACATGCACAGATGTTTGGCAGCTTCAAAAG
Seq C2 exon
GGATCGGGCTCCTTTTGTGCTGACCTCTGATATGGCATATGTCATTAATGGGGGTGAAAAGCCCACCATTCGTTTTCAGTTGTTTGTGGACCTCTGCTGTCAGGCCTACAACTTGATAAGAAAGCAGACAAACCTTTTTCTTAACCTCCTTTCACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011405-'23-25,'23-24,24-25=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0045422=PI3_PI4_kinase=FE(20.8=100)
A:
PF0045422=PI3_PI4_kinase=FE(25.9=100)
C2:
PF0045422=PI3_PI4_kinase=FE(24.1=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGGTTCCTGCTTCCGATAC
R:
CAAGTTGTAGGCCTGACAGCA
Band lengths:
242-412
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)