HsaEX6014155 @ hg38
Exon Skipping
Gene
ENSG00000115423 | DNAH6
Description
dynein axonemal heavy chain 6 [Source:HGNC Symbol;Acc:HGNC:2951]
Coordinates
chr2:84785610-84796425:+
Coord C1 exon
chr2:84785610-84785756
Coord A exon
chr2:84787164-84787302
Coord C2 exon
chr2:84796306-84796425
Length
139 bp
Sequences
Splice sites
3' ss Seq
ATTTTCATTTTTCATTTTAGGAG
3' ss Score
10.83
5' ss Seq
CTGGTGAGT
5' ss Score
10.1
Exon sequences
Seq C1 exon
GTGACCAATGAGCCTCCAAAAGGCTTACGTGCAAATATCAGACGAGCATTTACTGAAATGACACCTTCGTTTTTTGAAGAAAATATACTTGGAAAAAAATGGAGACAAATAATATTTGGCATTTGTTTCTTCCATGCAATTATTCAG
Seq A exon
GAGAGAAAGAAGTTTGGCCCCCTTGGTTGGAATATCTGCTATGAATTTAATGACAGTGACAGGGAATGTGCTTTACTGAATCTCAAACTCTATTGTAAAGAAGGAAAGATTCCCTGGGATGCACTAATTTACATTACTG
Seq C2 exon
GTGAAATTACTTATGGTGGTAGAGTCACAGACAGCTGGGACCAAAGATGCCTTCGTACTATCTTGAAAAGATTTTTTTCTCCTGAAACATTAGAAGAAGATTATAAATACTCTGAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115423-'89-94,'89-91,90-94
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(11.2=100)
A:
PF0302810=Dynein_heavy=FE(10.7=100)
C2:
PF0302810=Dynein_heavy=FE(5.3=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGACCAATGAGCCTCCAAAAG
R:
TCTTTTCAAGATAGTACGAAGGCA
Band lengths:
218-357
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains