HsaEX6015425 @ hg19
Exon Skipping
Gene
ENSG00000169994 | MYO7B
Description
myosin VIIB [Source:HGNC Symbol;Acc:7607]
Coordinates
chr2:128388353-128389328:+
Coord C1 exon
chr2:128388353-128388483
Coord A exon
chr2:128388781-128388938
Coord C2 exon
chr2:128389175-128389328
Length
158 bp
Sequences
Splice sites
3' ss Seq
ACCAGCCTCTAACCTCACAGGGC
3' ss Score
7.42
5' ss Seq
TCGATATCC
5' ss Score
-5.09
Exon sequences
Seq C1 exon
AGCTTGCTTGCCATGTCACCAGAGAAGAGGAAGCTGGCGGCTCAGGAGGGGCAGTTCACAGAGCCACGTCCTGAGGAGCCACCCAAGGAAAAGCTGCACACCCTGGAGGAGTTCTCCTATGAGTTCTTCAG
Seq A exon
GGCTCCAGAGAAGGACATGGTGAGCATGGCCGTGCTGCCCCTGGCCCGTGCCCGTGGCCACCTGTGGGCCTATTCCTGCGAGCCGCTGCGACAGCCGCTGCTCAAGCGAGTCCACGCCAACGTCGACCTCTGGGACATCGCCTGCCAGATCTTTGTCG
Seq C2 exon
CCATCCTCCGGTACATGGGCGACTACCCTTCTCGGCAGGCCTGGCCCACCCTGGAGCTCACCGACCAGATCTTCACACTGGCCCTGCAGCACCCGGCCCTCCAGGACGAGGTCTACTGCCAGATCCTGAAGCAGCTGACGCACAACTCCAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169994-'43-50,'43-48,45-50=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.420 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0078412=MyTH4=PU(34.0=69.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTTGCCATGTCACCAGAGAA
R:
ATCTGGCAGTAGACCTCGTCC
Band lengths:
250-408
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)