HsaEX6015450 @ hg19
Exon Skipping
Gene
ENSG00000169994 | MYO7B
Description
myosin VIIB [Source:HGNC Symbol;Acc:7607]
Coordinates
chr2:128341697-128346130:+
Coord C1 exon
chr2:128341697-128341907
Coord A exon
chr2:128342353-128342488
Coord C2 exon
chr2:128345967-128346130
Length
136 bp
Sequences
Splice sites
3' ss Seq
GGGTGTCTGGGTTCTTCCAGGGG
3' ss Score
7.57
5' ss Seq
AAGGTGGGT
5' ss Score
8.23
Exon sequences
Seq C1 exon
CTTCGAGCAGCTCTGCATCAACTTCGCCAACGAGCACCTGCAGCAGTTCTTTGTGCAGCACGTGTTCACCATGGAGCAAGAGGAGTACCGCTCGGAGAACATCTCCTGGGACTATATCCACTACACCGACAATCGGCCCACCCTGGACCTGCTGGCCCTCAAGCCCATGAGCATCATCTCCCTCCTGGACGAAGAAAGCCGCTTCCCGCAG
Seq A exon
GGGACAGATCTCACCATGCTGCAAAAGCTGAACAGCGTCCATGCCAACAACAAGGCCTTCCTACAGCCCAAGAACATCCACGATGCCAGATTTGGCATTGCCCATTTTGCCGGCGAGGTGTACTACCAAGCAGAAG
Seq C2 exon
GCTTCCTGGAGAAGAACCGAGACGTGCTGAGCACAGATATCCTCACCCTGGTTTACTCCTCCAAAAACAAGTTTCTGAGGGAGATATTCAACTTGGAGTTAGCAGAGACCAAGCTGGGCCATGGGACCATCCGCCAGGCAAAGGCAGGAAACCATCTCTTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169994-'12-14,'12-13,13-14=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.018
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(10.3=100)
A:
PF0006316=Myosin_head=FE(6.6=100)
C2:
PF0006316=Myosin_head=FE(7.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTACCGCTCGGAGAACATCT
R:
CCCAGCTTGGTCTCTGCTAAC
Band lengths:
246-382
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)