HsaEX6015728 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:140993995-141013745:-
Coord C1 exon
chr2:141013556-141013745
Coord A exon
chr2:141005335-141005457
Coord C2 exon
chr2:140993995-140994135
Length
123 bp
Sequences
Splice sites
3' ss Seq
TTGCTTTCTTCCTCTTGCAGGTG
3' ss Score
13.72
5' ss Seq
CATGTAAGT
5' ss Score
8.31
Exon sequences
Seq C1 exon
ATTGTTTACAGTGGGAGAGAGTTGAACCACCCTTTCGGACTGTCGCATCATGGAAATTATGTGTTCTGGACTGATTATATGAATGGTTCCATTTTTCAACTAGATTTGATAACAAGTGAGGTGACATTGCTGAGGCATGAAAGACCACCCCTATTTGGGCTTCAGATTTATGATCCACGAAAGCAACAAG
Seq A exon
GTGACAATATGTGCCGAGTAAATAATGGGGGCTGTAGTACACTTTGCTTGGCTATCCCAGGAGGCCGGGTGTGTGCTTGTGCCGATAATCAACTTTTGGATGAAAATGGGACAACTTGCACAT
Seq C2 exon
TTAATCCTGGAGAAGCACTACCTCACATATGTAAAGCTGGAGAGTTTCGCTGCAAAAACAGACACTGTATCCAAGCTCGGTGGAAATGTGATGGCGACGATGACTGCCTAGACGGAAGCGATGAGGATTCAGTAAACTGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'28-52,'28-51,29-52=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(34.2=20.3)
A:
PF146701=FXa_inhibition=WD(100=85.7)
C2:
PF0005713=Ldl_recept_a=WD(100=81.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGACTGTCGCATCATGGAAA
R:
CACATTTCCACCGAGCTTGGA
Band lengths:
245-368
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains