MmuEX6101023 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:41449186-41469011:-
Coord C1 exon
chr2:41468822-41469011
Coord A exon
chr2:41458300-41458422
Coord C2 exon
chr2:41449186-41449326
Length
123 bp
Sequences
Splice sites
3' ss Seq
TCTTTCTTTTTTTTCTGCAGGTG
3' ss Score
13.63
5' ss Seq
CGTGTAAGT
5' ss Score
8.58
Exon sequences
Seq C1 exon
GTTGTATACAGTGGTAAAGAGCTGAACCATCCTTTTGGACTGTCACATCATGGGAATTATGTGTTCTGGACAGATTACATGAATGGTTCAATTTTTCAACTAGATTTGATGACCAATGAGGTGACGTTGCTGAGGCATGAAAGAGCACCCCTGTTTGGGCTTCAGATTTATGATCCACGAAAACAACAAG
Seq A exon
GTGACAATATGTGCCGCATTAACAATGGGGGCTGTGGCACCCTCTGCCTGGCCATTCCAGCAGGCCGAGTGTGTGCTTGTGCTGATAATCAACTTTTGGATGAAAATGGAACTACTTGCACGT
Seq C2 exon
TTAATCCTGAAGAAATAAGGTTTCATATCTGTAAACCTGGAGAATTTCGCTGCAAGAACAAACACTGTATCCAAGCACGATGGAAATGTGACGGCGACGATGACTGCCTAGACGGGAGTGATGAGGACTCTGTCACATGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'30-26,'30-24,31-26
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PD(34.2=20.3)
A:
PF146701=FXa_inhibition=WD(100=85.7)
C2:
PF0005713=Ldl_recept_a=WD(100=81.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGACTGTCACATCATGGGAA
R:
CCGTCACATTTCCATCGTGCT
Band lengths:
249-372
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types