HsaEX6015734 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:140868099-140886335:-
Coord C1 exon
chr2:140886138-140886335
Coord A exon
chr2:140883817-140884021
Coord C2 exon
chr2:140868099-140868263
Length
205 bp
Sequences
Splice sites
3' ss Seq
TGGTTTTCCTTCTTTTGTAGGTG
3' ss Score
11.4
5' ss Seq
TGGGTAAAG
5' ss Score
4.2
Exon sequences
Seq C1 exon
ATCCTTTTGAAGCATTCATCATCTTTTCTATTCGTCATGAGATCAGAAGGATTGATCTTCACAAAAGAGACTATAGTCTACTTGTTCCTGGATTGAGAAACACAATAGCACTTGATTTTCACTTCAATCAAAGTTTACTTTATTGGACAGATGTTGTAGAAGACAGAATATACCGGGGAAAGCTTTCTGAAAGTGGAG
Seq A exon
GTGTCAGTGCCATTGAAGTGGTTGTGGAGCATGGCCTGGCTACTCCAGAAGGCCTGACAGTCGACTGGATAGCAGGAAACATATACTGGATAGACAGCAATCTGGACCAAATCGAAGTGGCCAAACTAGATGGCTCCCTAAGAACTACACTAATAGCAGGAGCCATGGAACACCCCAGGGCCATTGCTTTGGACCCAAGATATGG
Seq C2 exon
AATTCTTTTCTGGACAGACTGGGATGCAAATTTTCCTCGCATTGAATCTGCCTCTATGAGTGGTGCTGGGAGAAAAACCATCTATAAAGACATGAAAACTGGGGCTTGGCCTAATGGACTAACTGTGGACCACTTTGAGAAAAGGATAGTGTGGACAGACGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'41-70,'41-69,42-70
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PU(48.9=32.8)
A:
PF0005812=Ldl_recept_b=PD(48.9=31.9),PF0005812=Ldl_recept_b=WD(100=59.4),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=80.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCGTCATGAGATCAGAAGGATTGA
R:
TCCACAGTTAGTCCATTAGGCCA
Band lengths:
296-501
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains