MmuEX6101032 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:41295996-41312673:-
Coord C1 exon
chr2:41312476-41312673
Coord A exon
chr2:41302805-41303009
Coord C2 exon
chr2:41295996-41296160
Length
205 bp
Sequences
Splice sites
3' ss Seq
TGGCTTCCTCTTTTTCACAGGTG
3' ss Score
10.64
5' ss Seq
TGGGTAAGA
5' ss Score
8.91
Exon sequences
Seq C1 exon
ATTCTTTTGAGGCATTCATCATCTTTTCTATACGCCATGAAATTCGAAGGATTGATCTGCATAAAGGAGACTACAGCCTACTTGTTCCTGGACTGAGAAATACCATAGCACTTGATTTTCACTTCAATCAAAGTTTACTTTACTGGACAGATGTTGTGGAAGACAGAATATACAGGGGCAAGCTGTCAGAGAGTGGAG
Seq A exon
GTGTCAGTGCCATAGAAGTGGTTGTGGAACATGGCTTGGCAACCCCAGAAGGCCTGACGGTTGACTGGATAGCTGGCAACATTTATTGGATAGATAGCAATCTGGACCAAATTGAAGTGTCTAAACTTGATGGTTCCCTGAGGGCTACACTAATAGCAGGAGCCATGGAGCATCCCAGGGCCATAGCACTGGATCCAAGATATGG
Seq C2 exon
AATTCTTTTCTGGACAGACTGGGATGCCAATTTCCCTCGCATTGAATCTGCTTCAATGAGTGGTGCCGGAAGAAAAACCATCTATAAAGACATGAAAACTGGGGCATGGCCTAATGGACTGACCGTGGACCACTTTGAAAGAAGAATAGTTTGGACGGATGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'44-40,'44-39,45-40
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=PU(48.9=32.8)
A:
PF0005812=Ldl_recept_b=PD(48.9=31.9),PF0005812=Ldl_recept_b=WD(100=59.4),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=80.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGCCATGAAATTCGAAGGAT
R:
CAAAGTGGTCCACGGTCAGTC
Band lengths:
304-509
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types