HsaEX6015743 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:140716682-140771006:-
Coord C1 exon
chr2:140770881-140771006
Coord A exon
chr2:140769213-140769344
Coord C2 exon
chr2:140716682-140716816
Length
132 bp
Sequences
Splice sites
3' ss Seq
ATCTCCGGCCCTGCATTTAGGTA
3' ss Score
8.82
5' ss Seq
CAGGTAAAT
5' ss Score
8.76
Exon sequences
Seq C1 exon
GCAGCAATTCCTGCCAACTAAACAATGGTGGATGCTCTCAACTTTGTTTACCAACATCTGAAACTACAAGGACTTGTATGTGTACAGTGGGATATTATCTCCAAAAGAACCGTATGTCATGTCAAG
Seq A exon
GTATAGAATCATTTCTTATGTACTCTGTTCATGAAGGAATCAGGGGAATACCTCTTGAACCAAGTGACAAAATGGATGCTTTGATGCCTATATCAGGAACTTCATTTGCCGTGGGAATAGATTTCCATGCAG
Seq C2 exon
AAAATGATACCATCTACTGGACAGACATGGGCTTCAATAAAATTAGCAGAGCTAAAAGAGATCAGACTTGGAAAGAAGATATCATTACCAATGGCTTGGGAAGAGTGGAAGGGATAGCTGTTGACTGGATTGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'60-89,'60-85,61-89=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=86.0)
A:
NO
C2:
PF0005812=Ldl_recept_b=WD(100=89.1),PF0005812=Ldl_recept_b=PU(0.1=0.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGCCAACTAAACAATGGTGG
R:
CCAGTCAACAGCTATCCCTTCC
Band lengths:
245-377
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains