HsaEX6015825 @ hg38
Exon Skipping
Gene
ENSG00000121989 | ACVR2A
Description
activin A receptor type 2A [Source:HGNC Symbol;Acc:HGNC:173]
Coordinates
chr2:147896301-147915334:+
Coord C1 exon
chr2:147896301-147896508
Coord A exon
chr2:147899458-147899567
Coord C2 exon
chr2:147915191-147915334
Length
110 bp
Sequences
Splice sites
3' ss Seq
TTTTCTCTGCTTATTTATAGGAC
3' ss Score
9.91
5' ss Seq
AGCGTAAGT
5' ss Score
10.07
Exon sequences
Seq C1 exon
GTGCTATACTTGGTAGATCAGAAACTCAGGAGTGTCTTTTCTTTAATGCTAATTGGGAAAAAGACAGAACCAATCAAACTGGTGTTGAACCGTGTTATGGTGACAAAGATAAACGGCGGCATTGTTTTGCTACCTGGAAGAATATTTCTGGTTCCATTGAAATAGTGAAACAAGGTTGTTGGCTGGATGATATCAACTGCTATGACAG
Seq A exon
GACTGATTGTGTAGAAAAAAAAGACAGCCCTGAAGTATATTTTTGTTGCTGTGAGGGCAATATGTGTAATGAAAAGTTTTCTTATTTTCCGGAGATGGAAGTCACACAGC
Seq C2 exon
GACCCAGGACCACCCCCACCTTCTCCATTACTAGGTTTGAAACCACTGCAGTTATTAGAAGTGAAAGCAAGGGGAAGATTTGGTTGTGTCTGGAAAGCCCAGTTGCTTAACGAATATGTGGCTGTCAAAATATTTCCAATACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000121989_MULTIEX1-5/8=3-8
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.024 C2=0.025
Domain overlap (PFAM):
C1:
PF0106418=Activin_recp=PU(65.9=85.7)
A:
PF0106418=Activin_recp=PD(33.0=78.9)
C2:
PF0006920=Pkinase=PU(11.1=66.7)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGACAGAACCAATCAAACTGGTGT
R:
GGGCTTTCCAGACACAACCAA
Band lengths:
247-357
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains