HsaEX6021011 @ hg19
Exon Skipping
Gene
ENSG00000133020 | MYH8
Description
myosin, heavy chain 8, skeletal muscle, perinatal [Source:HGNC Symbol;Acc:7578]
Coordinates
chr17:10302085-10304096:-
Coord C1 exon
chr17:10303707-10304096
Coord A exon
chr17:10302860-10302986
Coord C2 exon
chr17:10302085-10302203
Length
127 bp
Sequences
Splice sites
3' ss Seq
CATTGCTACATATCCTGTAGGGA
3' ss Score
7.06
5' ss Seq
CGGGTAAAG
5' ss Score
6.23
Exon sequences
Seq C1 exon
GCCCGCATTGAGGAGCTGGGGGAAGAAATCGAGGCAGAGAGGGCGTCCCGAGCCAAAGCGGAGAAGCAGCGCTCTGACCTCTCCCGGGAACTGGAGGAGATCAGCGAGAGGCTGGAAGAAGCCGGTGGGGCAACTTCTGCTCAGGTGGAATTGAACAAGAAGCGGGAGGCTGAGTTTCAGAAACTGCGCAGGGACCTGGAGGAGGCCACCCTGCAGCATGAAGCTATGGTGGCTGCTCTTCGGAAGAAGCACGCAGACAGTATGGCTGAGCTTGGGGAGCAGATTGACAACTTGCAGCGGGTCAAACAGAAGCTGGAGAAGGAGAAGAGTGAGCTGAAGATGGAGACTGATGACCTCAGCAGTAACGCAGAGGCCATTTCCAAAGCCAAG
Seq A exon
GGAAACCTTGAAAAGATGTGCCGCTCTCTAGAAGATCAAGTGAGTGAGCTTAAGACCAAGGAAGAGGAGCAGCAGCGGCTGATCAATGACCTCACAGCACAGAGAGCGCGCCTGCAGACAGAAGCGG
Seq C2 exon
GTGAATATTCTCGACAATTAGATGAGAAAGATGCTTTAGTCTCTCAGCTTTCAAGGAGCAAGCAAGCATCTACTCAGCAGATTGAAGAGCTGAAACATCAACTAGAGGAAGAAACTAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133020-'26-28,'26-27,27-28=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.838 A=0.884 C2=0.950
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(15.0=100)
A:
PF0157614=Myosin_tail_1=FE(4.9=100)
C2:
PF0157614=Myosin_tail_1=FE(4.5=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATGAAGCTATGGTGGCTGCT
R:
AGATGCTTGCTTGCTCCTTGA
Band lengths:
245-372
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)