HsaEX6021011 @ hg38
Exon Skipping
Gene
ENSG00000133020 | MYH8
Description
myosin heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:7578]
Coordinates
chr17:10398768-10400779:-
Coord C1 exon
chr17:10400390-10400779
Coord A exon
chr17:10399543-10399669
Coord C2 exon
chr17:10398768-10398886
Length
127 bp
Sequences
Splice sites
3' ss Seq
CATTGCTACATATCCTGTAGGGA
3' ss Score
7.06
5' ss Seq
CGGGTAAAG
5' ss Score
6.23
Exon sequences
Seq C1 exon
GCCCGCATTGAGGAGCTGGGGGAAGAAATCGAGGCAGAGAGGGCGTCCCGAGCCAAAGCGGAGAAGCAGCGCTCTGACCTCTCCCGGGAACTGGAGGAGATCAGCGAGAGGCTGGAAGAAGCCGGTGGGGCAACTTCTGCTCAGGTGGAATTGAACAAGAAGCGGGAGGCTGAGTTTCAGAAACTGCGCAGGGACCTGGAGGAGGCCACCCTGCAGCATGAAGCTATGGTGGCTGCTCTTCGGAAGAAGCACGCAGACAGTATGGCTGAGCTTGGGGAGCAGATTGACAACTTGCAGCGGGTCAAACAGAAGCTGGAGAAGGAGAAGAGTGAGCTGAAGATGGAGACTGATGACCTCAGCAGTAACGCAGAGGCCATTTCCAAAGCCAAG
Seq A exon
GGAAACCTTGAAAAGATGTGCCGCTCTCTAGAAGATCAAGTGAGTGAGCTTAAGACCAAGGAAGAGGAGCAGCAGCGGCTGATCAATGACCTCACAGCACAGAGAGCGCGCCTGCAGACAGAAGCGG
Seq C2 exon
GTGAATATTCTCGACAATTAGATGAGAAAGATGCTTTAGTCTCTCAGCTTTCAAGGAGCAAGCAAGCATCTACTCAGCAGATTGAAGAGCTGAAACATCAACTAGAGGAAGAAACTAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133020-'28-27,'28-26,29-27=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.838 A=0.884 C2=0.950
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(15.0=100)
A:
PF0157614=Myosin_tail_1=FE(4.9=100)
C2:
PF0157614=Myosin_tail_1=FE(4.5=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATGAAGCTATGGTGGCTGCT
R:
AGATGCTTGCTTGCTCCTTGA
Band lengths:
245-372
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains