HsaEX6021012 @ hg19
Exon Skipping
Gene
ENSG00000133020 | MYH8
Description
myosin, heavy chain 8, skeletal muscle, perinatal [Source:HGNC Symbol;Acc:7578]
Coordinates
chr17:10301761-10302986:-
Coord C1 exon
chr17:10302860-10302986
Coord A exon
chr17:10302085-10302203
Coord C2 exon
chr17:10301761-10301957
Length
119 bp
Sequences
Splice sites
3' ss Seq
CTTATGTCTATTATTCCTAGGTG
3' ss Score
7.56
5' ss Seq
AAAGTGAGT
5' ss Score
8.4
Exon sequences
Seq C1 exon
GGAAACCTTGAAAAGATGTGCCGCTCTCTAGAAGATCAAGTGAGTGAGCTTAAGACCAAGGAAGAGGAGCAGCAGCGGCTGATCAATGACCTCACAGCACAGAGAGCGCGCCTGCAGACAGAAGCGG
Seq A exon
GTGAATATTCTCGACAATTAGATGAGAAAGATGCTTTAGTCTCTCAGCTTTCAAGGAGCAAGCAAGCATCTACTCAGCAGATTGAAGAGCTGAAACATCAACTAGAGGAAGAAACTAAA
Seq C2 exon
GCCAAGAACGCCCTGGCACACGCCCTGCAGTCCTCCCGCCATGACTGCGACCTGCTGCGGGAACAGTATGAGGAAGAGCAGGAAGGCAAAGCTGAGCTGCAGAGGGCGCTGTCCAAGGCCAACAGTGAGGTTGCCCAGTGGAGAACCAAATACGAGACGGATGCCATCCAGCGCACAGAGGAGCTGGAGGAGGCCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133020-'27-29,'27-28,28-29=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.884 A=0.950 C2=0.591
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(4.9=100)
A:
PF0157614=Myosin_tail_1=FE(4.5=100)
C2:
PF0157614=Myosin_tail_1=FE(7.6=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCTTGAAAAGATGTGCCGCT
R:
CTCACTGTTGGCCTTGGACAG
Band lengths:
252-371
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)