HsaEX6021018 @ hg19
Exon Skipping
Gene
ENSG00000133020 | MYH8
Description
myosin, heavy chain 8, skeletal muscle, perinatal [Source:HGNC Symbol;Acc:7578]
Coordinates
chr17:10295199-10296318:-
Coord C1 exon
chr17:10296148-10296318
Coord A exon
chr17:10295859-10295963
Coord C2 exon
chr17:10295199-10295294
Length
105 bp
Sequences
Splice sites
3' ss Seq
AGTATTTTTCTTGGCTGCAGGTA
3' ss Score
7.41
5' ss Seq
CAGGTAAAG
5' ss Score
9.65
Exon sequences
Seq C1 exon
GCTGCCATGATGGCTGAGGAGCTGAAGAAGGAACAGGACACCAGCGCCCACCTGGAGCGGATGAAGAAGAACCTGGAGCAGACGGTGAAGGACCTGCAGCATCGTCTAGATGAGGCCGAGCAGCTGGCGCTGAAGGGTGGGAAGAAGCAGATCCAGAAACTGGAGGCCAGG
Seq A exon
GTACGTGAGCTTGAAGGAGAGGTTGAAAATGAACAGAAACGTAATGCAGAGGCTGTTAAAGGTTTACGGAAACATGAGCGACGAGTAAAAGAACTCACCTACCAG
Seq C2 exon
ACTGAAGAAGATCGCAAGAATGTTCTCAGGCTGCAGGACTTGGTAGATAAATTACAGGCGAAGGTGAAATCATACAAGAGACAAGCTGAGGAGGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133020-'36-38,'36-37,37-38=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.754 A=0.971 C2=0.250
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(6.5=100)
A:
PF0157614=Myosin_tail_1=FE(4.0=100)
C2:
PF0157614=Myosin_tail_1=FE(3.6=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCTGAGGAGCTGAAGAAGGA
R:
AGCCTCCTCAGCTTGTCTCTT
Band lengths:
256-361
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)