HsaEX6021063 @ hg19
Exon Skipping
Gene
ENSG00000125414 | MYH2
Description
myosin, heavy chain 2, skeletal muscle, adult [Source:HGNC Symbol;Acc:7572]
Coordinates
chr17:10442761-10444014:-
Coord C1 exon
chr17:10443911-10444014
Coord A exon
chr17:10443245-10443383
Coord C2 exon
chr17:10442761-10442879
Length
139 bp
Sequences
Splice sites
3' ss Seq
CCTATTGGTTATATTGACAGAGT
3' ss Score
3.07
5' ss Seq
AAGGTATCA
5' ss Score
7.22
Exon sequences
Seq C1 exon
AAATGCTTCTGATTACCACGAACCCATATGATTACCCATTTGTCAGTCAAGGGGAGATCAGTGTGGCCAGCATCGATGATCAGGAAGAACTGATGGCCACAGAT
Seq A exon
AGTGCTATTGATATTTTGGGCTTTACTAATGAAGAAAAGGTCTCCATTTACAAGCTCACGGGGGCTGTGATGCATTATGGGAACCTAAAATTTAAGCAAAAGCAGCGTGAGGAGCAAGCAGAGCCAGATGGCACAGAAG
Seq C2 exon
TTGCTGACAAGGCGGCCTACCTCCAGAGTCTGAACTCTGCAGATCTGCTCAAAGCTCTCTGCTACCCCAGGGTCAAGGTCGGCAATGAGTATGTCACCAAAGGCCAGACTGTAGAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125414-'13-13,'13-12,14-13=AN
Average complexity
A_S
Mappability confidence:
100%=100=50%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.277 C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(5.0=100)
A:
PF0006316=Myosin_head=FE(6.7=100)
C2:
PF0006316=Myosin_head=FE(5.7=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCTTCTGATTACCACGAACCC
R:
GTTCTACAGTCTGGCCTTTGGT
Band lengths:
218-357
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)