HsaEX6021064 @ hg19
Exon Skipping
Gene
ENSG00000125414 | MYH2
Description
myosin, heavy chain 2, skeletal muscle, adult [Source:HGNC Symbol;Acc:7572]
Coordinates
chr17:10438595-10440859:-
Coord C1 exon
chr17:10440550-10440859
Coord A exon
chr17:10439847-10439923
Coord C2 exon
chr17:10438595-10438682
Length
77 bp
Sequences
Splice sites
3' ss Seq
TTTTCTTCCTTTTTCTTCAGAGG
3' ss Score
10.79
5' ss Seq
AGAGTAAGG
5' ss Score
5.42
Exon sequences
Seq C1 exon
CCTATGGGCATCTTCTCCATCCTGGAAGAGGAGTGCATGTTCCCTAAGGCAACAGACACCTCCTTCAAGAACAAGCTGTATGACCAGCACCTGGGCAAGTCTGCCAACTTCCAGAAGCCCAAGGTGGTCAAAGGCAAGGCCGAGGCCCACTTCGCTCTGATTCACTATGCTGGTGTTGTGGACTACAACATTACTGGCTGGCTGGAGAAGAACAAGGACCCCCTGAATGAGACCGTGGTTGGACTGTACCAGAAGTCTGCAATGAAAACTCTAGCTCAGCTCTTCTCTGGGGCTCAAACTGCTGAAGGAG
Seq A exon
AGGGAGCTGGTGGAGGGGCCAAGAAAGGTGGTAAGAAGAAGGGCTCTTCTTTCCAGACAGTGTCTGCCCTTTTCAGA
Seq C2 exon
GAGAATTTGAACAAGCTGATGACCAACCTCAGGAGTACCCATCCTCACTTTGTGAGGTGTATCATCCCCAATGAGACAAAAACTCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125414-'18-18,'18-17,19-18=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.010 A=0.449 C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(15.0=100)
A:
PF0006316=Myosin_head=FE(4.3=100),PF0157614=Myosin_tail_1=PU(2.3=3.8),PF0026115=Tropomyosin=PU(12.1=26.9)
C2:
PF0006316=Myosin_head=FE(4.2=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAACATTACTGGCTGGCTGG
R:
TGGGTACTCCTGAGGTTGGTC
Band lengths:
167-244
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)