HsaEX6021064 @ hg38
Exon Skipping
Gene
ENSG00000125414 | MYH2
Description
myosin heavy chain 2 [Source:HGNC Symbol;Acc:HGNC:7572]
Coordinates
chr17:10535278-10537542:-
Coord C1 exon
chr17:10537233-10537542
Coord A exon
chr17:10536530-10536606
Coord C2 exon
chr17:10535278-10535365
Length
77 bp
Sequences
Splice sites
3' ss Seq
TTTTCTTCCTTTTTCTTCAGAGG
3' ss Score
10.79
5' ss Seq
AGAGTAAGG
5' ss Score
5.42
Exon sequences
Seq C1 exon
CCTATGGGCATCTTCTCCATCCTGGAAGAGGAGTGCATGTTCCCTAAGGCAACAGACACCTCCTTCAAGAACAAGCTGTATGACCAGCACCTGGGCAAGTCTGCCAACTTCCAGAAGCCCAAGGTGGTCAAAGGCAAGGCCGAGGCCCACTTCGCTCTGATTCACTATGCTGGTGTTGTGGACTACAACATTACTGGCTGGCTGGAGAAGAACAAGGACCCCCTGAATGAGACCGTGGTTGGACTGTACCAGAAGTCTGCAATGAAAACTCTAGCTCAGCTCTTCTCTGGGGCTCAAACTGCTGAAGGAG
Seq A exon
AGGGAGCTGGTGGAGGGGCCAAGAAAGGTGGTAAGAAGAAGGGCTCTTCTTTCCAGACAGTGTCTGCCCTTTTCAGA
Seq C2 exon
GAGAATTTGAACAAGCTGATGACCAACCTCAGGAGTACCCATCCTCACTTTGTGAGGTGTATCATCCCCAATGAGACAAAAACTCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125414-'20-23,'20-21,22-23
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.014 A=0.462 C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(15.0=100)
A:
PF0006316=Myosin_head=FE(4.3=100),PF0157614=Myosin_tail_1=PU(2.3=3.8)
C2:
PF0006316=Myosin_head=FE(4.2=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAACATTACTGGCTGGCTGG
R:
TGGGTACTCCTGAGGTTGGTC
Band lengths:
167-244
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains