HsaEX6055160 @ hg19
Exon Skipping
Gene
ENSG00000185313 | SCN10A
Description
sodium channel, voltage-gated, type X, alpha subunit [Source:HGNC Symbol;Acc:10582]
Coordinates
chr3:38830447-38835501:-
Coord C1 exon
chr3:38835232-38835501
Coord A exon
chr3:38833541-38833659
Coord C2 exon
chr3:38830447-38830527
Length
119 bp
Sequences
Splice sites
3' ss Seq
TCTGTTTTGTTTTGTTTCAGACA
3' ss Score
10.9
5' ss Seq
CTCATATCC
5' ss Score
-13.36
Exon sequences
Seq C1 exon
ATGGAATTCCCCATTGGATCCCTCGAAACTAACAACTTCCGTCGCTTTACTCCGGAGTCACTGGTGGAGATAGAGAAGCAAATTGCTGCCAAGCAGGGAACAAAGAAAGCCAGAGAGAAGCATAGGGAGCAGAAGGACCAAGAAGAGAAGCCTCGGCCCCAGCTGGACTTGAAAGCCTGCAACCAGCTGCCCAAGTTCTATGGTGAGCTCCCAGCAGAACTGATCGGGGAGCCCCTGGAGGATCTAGATCCGTTCTACAGCACACACCGG
Seq A exon
ACATTTATGGTGCTGAACAAAGGGAGGACCATTTCCCGGTTTAGTGCCACTCGGGCCCTGTGGCTATTCAGTCCTTTCAACCTGATCAGAAGAACGGCCATCAAAGTGTCTGTCCACTC
Seq C2 exon
GTGGTTCAGTTTATTTATTACGGTCACTATTTTGGTTAATTGTGTGTGCATGACCCGAACTGACCTTCCAGAGAAAATTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185313-'0-1,'0-0,1-1=AN
Average complexity
A_NA
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.289 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0052026=Ion_trans=PU(0.8=7.1)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCAAGCAGGGAACAAAGAA
R:
TGGAAGGTCAGTTCGGGTCAT
Band lengths:
254-373
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)