HsaEX6063131 @ hg38
Exon Skipping
Gene
ENSG00000136807 | CDK9
Description
cyclin dependent kinase 9 [Source:HGNC Symbol;Acc:HGNC:1780]
Coordinates
chr9:127786701-127788113:+
Coord C1 exon
chr9:127786701-127786782
Coord A exon
chr9:127787518-127787608
Coord C2 exon
chr9:127787947-127788113
Length
91 bp
Sequences
Splice sites
3' ss Seq
TTCCCCTCTTTCTCACCCAGTTC
3' ss Score
9.06
5' ss Seq
AAGGTAAGT
5' ss Score
11
Exon sequences
Seq C1 exon
GGAGGTGTTCAAGGCCAGGCACCGCAAGACCGGCCAGAAGGTGGCTCTGAAGAAGGTGCTGATGGAAAACGAGAAGGAGGGG
Seq A exon
TTCCCCATTACAGCCTTGCGGGAGATCAAGATCCTTCAGCTTCTAAAACACGAGAATGTGGTCAACTTGATTGAGATTTGTCGAACCAAAG
Seq C2 exon
CTTCCCCCTATAACCGCTGCAAGGGTAGTATATACCTGGTGTTCGACTTCTGCGAGCATGACCTTGCTGGGCTGTTGAGCAATGTTTTGGTCAAGTTCACGCTGTCTGAGATCAAGAGGGTGATGCAGATGCTGCTTAACGGCCTCTACTACATCCACAGAAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136807-'4-5,'4-2,7-5
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.083 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(32.1=100)
A:
PF0006920=Pkinase=FE(10.1=100)
C2:
PF0006920=Pkinase=FE(18.5=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGCTCTGAAGAAGGTGCTG
R:
AGCATCTGCATCACCCTCTTG
Band lengths:
175-266
Functional annotations
There are 1 annotated functions for this event
PMID: 23140174
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, protein kinase assay, western blot. ELM ID: ELMI003213; ELM sequence: TKASPYNR; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains