HsaEX6065073 @ hg19
Exon Skipping
Gene
ENSG00000175899 | A2M
Description
alpha-2-macroglobulin [Source:HGNC Symbol;Acc:7]
Coordinates
chr12:9241796-9243078:-
Coord C1 exon
chr12:9242952-9243078
Coord A exon
chr12:9242498-9242619
Coord C2 exon
chr12:9241796-9241847
Length
122 bp
Sequences
Splice sites
3' ss Seq
CTACTGGCCTTTTTTTTCAGGAA
3' ss Score
10.27
5' ss Seq
GAAGTAAGT
5' ss Score
9.82
Exon sequences
Seq C1 exon
GTCAGTGTGCAGCTGGAAGCCTCTCCCGCCTTCCTAGCTGTCCCAGTGGAGAAGGAACAAGCGCCTCACTGCATCTGTGCAAACGGGCGGCAAACTGTGTCCTGGGCAGTAACCCCAAAGTCATTAG
Seq A exon
GAAATGTGAATTTCACTGTGAGCGCAGAGGCACTAGAGTCTCAAGAGCTGTGTGGGACTGAGGTGCCTTCAGTTCCTGAACACGGAAGGAAAGACACAGTCATCAAGCCTCTGTTGGTTGAA
Seq C2 exon
CCTGAAGGACTAGAGAAGGAAACAACATTCAACTCCCTACTTTGTCCATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175899-'32-39,'32-38,33-39=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.146 C2=0.056
Domain overlap (PFAM):
C1:
PF0020717=A2M=PD(6.6=11.6)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCAGTGTGCAGCTGGAAGC
R:
TGATGGACAAAGTAGGGAGTTGA
Band lengths:
178-300
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)