HsaEX6065103 @ hg38
Exon Skipping
Gene
ENSG00000126838 | PZP
Description
PZP, alpha-2-macroglobulin like [Source:HGNC Symbol;Acc:HGNC:9750]
Coordinates
chr12:9164133-9166202:-
Coord C1 exon
chr12:9166052-9166202
Coord A exon
chr12:9165139-9165367
Coord C2 exon
chr12:9164133-9164259
Length
229 bp
Sequences
Splice sites
3' ss Seq
TCACTTGCCCTCCTCCCCAGCTC
3' ss Score
8.84
5' ss Seq
CGGGTAAGG
5' ss Score
10.17
Exon sequences
Seq C1 exon
CAGGTCTAGGAGTAGTAGAGAGACCATATGTTCCTCAATTAGGCACATATAATGTGATACCCTTAAATAATGAACAAAGTTCAGGGCCAGTCCCTGAAACGGTGCGAAGCTATTTTCCTGAGACTTGGATCTGGGAGTTGGTGGCAGTGAA
Seq A exon
CTCATCAGGTGTGGCTGAGGTAGGAGTAACAGTCCCTGACACCATCACCGAGTGGAAGGCAGGGGCCTTCTGCCTGTCCGAAGATGCTGGACTTGGTATCTCTTCCACTGCCTCTCTCCGAGCCTTCCAGCCCTTCTTTGTGGAGCTCACAATGCCTTACTCTGTGATTCGTGGAGAGGTCTTCACACTCAAGGCCACGGTCCTAAACTACCTTCCCAAATGCATCCGG
Seq C2 exon
GTCAGTGTGCAGCTGAAAGCCTCTCCAGCCTTCCTAGCTTCCCAAAATACAAAGGGAGAAGAATCCTATTGTATCTGTGGAAATGAGAGACAAACCTTGTCTTGGACAGTGACTCCTAAAACTCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126838-'25-25,'25-24,26-25=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0020717=A2M=PU(9.9=17.6)
A:
PF0020717=A2M=FE(83.5=100)
C2:
PF0020717=A2M=PD(4.4=9.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGTCTAGGAGTAGTAGAGAGACCA
R:
CCAGAGTTTTAGGAGTCACTGTCC
Band lengths:
277-506
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains