HsaEX6065108 @ hg38
Exon Skipping
Gene
ENSG00000126838 | PZP
Description
PZP, alpha-2-macroglobulin like [Source:HGNC Symbol;Acc:HGNC:9750]
Coordinates
chr12:9158420-9160490:-
Coord C1 exon
chr12:9160314-9160490
Coord A exon
chr12:9159938-9160025
Coord C2 exon
chr12:9158420-9158576
Length
88 bp
Sequences
Splice sites
3' ss Seq
TCTGAAGCCTTCCATTTCAGGTT
3' ss Score
6.7
5' ss Seq
TTGGTAAGA
5' ss Score
8.85
Exon sequences
Seq C1 exon
GTGACATATTAGGTTCTGCTATGCAAAATATACAAAATCTCCTCCAGATGCCATATGGCTGTGGAGAACAGAACATGGTCCTATTTGCTCCTAACATCTATGTCTTGAACTATCTGAATGAAACCCAGCAGCTGACGCAGGAGATCAAGGCCAAGGCCGTTGGCTATCTCATCACTG
Seq A exon
GTTACCAGAGACAGCTGAACTACAAACACCAAGATGGCTCCTACAGCACCTTTGGGGAACGATATGGCAGGAACCAGGGCAACACTTG
Seq C2 exon
GCTCACAGCTTTTGTACTGAAGACTTTCGCCCAGGCTCGATCCTACATCTTCATTGATGAAGCACACATTACCCAATCTCTCACGTGGCTCTCCCAGATGCAGAAGGACAATGGCTGTTTCAGGAGCTCTGGGTCACTGCTCAACAATGCCATAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126838-'37-34,'37-32,38-34=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.033 C2=0.000
Domain overlap (PFAM):
C1:
PF105694=Thiol-ester_cl=WD(100=51.7),PF076789=A2M_comp=PU(0.4=1.7)
A:
PF076789=A2M_comp=FE(11.3=100)
C2:
PF076789=A2M_comp=FE(20.2=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCTGACGCAGGAGATCAAG
R:
AACAGCCATTGTCCTTCTGCA
Band lengths:
168-256
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains