HsaEX6065112 @ hg38
Exon Skipping
Gene
ENSG00000126838 | PZP
Description
PZP, alpha-2-macroglobulin like [Source:HGNC Symbol;Acc:HGNC:9750]
Coordinates
chr12:9153125-9157355:-
Coord C1 exon
chr12:9157175-9157355
Coord A exon
chr12:9154616-9154839
Coord C2 exon
chr12:9153125-9153343
Length
224 bp
Sequences
Splice sites
3' ss Seq
TCCTTTTTCTCACCCTTAAGACA
3' ss Score
5.28
5' ss Seq
CAGGTCAGT
5' ss Score
8.94
Exon sequences
Seq C1 exon
AACCCTATTGTTCGCAATGCCCTGTTCTGCCTGGAGTCAGCCTGGAATGTAGCAAAGGAGGGGACCCATGGGAGCCATGTCTACACCAAGGCATTGCTGGCCTATGCTTTTTCCCTACTGGGAAAGCAAAATCAGAATAGAGAAATACTGAACTCACTTGATAAGGAAGCTGTGAAAGAAG
Seq A exon
ACAACCTCGTCCATTGGGAGCGCCCTCAGAGACCCAAGGCACCAGTGGGGCATCTTTACCAAACCCAGGCTCCCTCTGCTGAGGTGGAGATGACATCCTATGTGCTCCTCGCTTATCTCACGGCCCAGCCAGCCCCCACCTCAGGGGACCTGACCTCTGCAACTAACATTGTGAAGTGGATCATGAAGCAGCAGAACGCCCAAGGTGGTTTCTCCTCCACCCAG
Seq C2 exon
GACACAGTGGTGGCTCTCCATGCCCTGTCCAGGTATGGAGCAGCCACTTTCACCAGAACTGAGAAAACTGCACAGGTCACCGTTCAGGATTCACAGACCTTTTCTACAAATTTCCAAGTAGACAACAACAACCTCCTATTACTGCAGCAGATCTCATTGCCAGAGCTCCCTGGAGAATATGTCATAACAGTAACTGGGGAAAGATGTGTGTATCTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126838-'41-42,'41-41,43-42=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.049 A=0.227 C2=0.014
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(23.3=100)
A:
PF076789=A2M_comp=FE(28.8=100)
C2:
PF076789=A2M_comp=PD(5.1=17.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAATGTAGCAAAGGAGGGGA
R:
TGGCAATGAGATCTGCTGCAG
Band lengths:
301-525
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains