HsaEX6065163 @ hg19
Exon Skipping
Gene
ENSG00000134539 | KLRD1
Description
killer cell lectin-like receptor subfamily D, member 1 [Source:HGNC Symbol;Acc:6378]
Coordinates
chr12:10462225-10466112:+
Coord C1 exon
chr12:10462225-10462287
Coord A exon
chr12:10464063-10464214
Coord C2 exon
chr12:10466009-10466112
Length
152 bp
Sequences
Splice sites
3' ss Seq
TGCTTTATGTTTTCTGTCAGACT
3' ss Score
7.31
5' ss Seq
CTGGCATGT
5' ss Score
0.38
Exon sequences
Seq C1 exon
CTTTTACTAAACTGAGTATTGAGCCAGCATTTACTCCAGGACCCAACATAGAACTCCAGAAAG
Seq A exon
ACTCTGACTGCTGTTCTTGCCAAGAAAAATGGGTTGGGTACCGGTGCAACTGTTACTTCATTTCCAGTGAACAGAAAACTTGGAACGAAAGTCGGCATCTCTGTGCTTCTCAGAAATCCAGCCTGCTTCAGCTTCAAAACACAGATGAACTG
Seq C2 exon
GATTTTATGAGCTCCAGTCAACAATTTTACTGGATTGGACTCTCTTACAGTGAGGAGCACACCGCCTGGTTGTGGGAGAATGGCTCTGCACTCTCCCAGTATCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134539-'2-4,'2-2,3-4=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF052948=Toxin_5=PU(45.5=68.2),PF059667=Chordopox_A33R=FE(22.6=100)
A:
PF078226=Toxin_13=PD(86.1=60.8),PF0005916=Lectin_C=PU(27.3=52.9)
C2:
PF0005916=Lectin_C=FE(34.3=100)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTAAACTGAGTATTGAGCCAGCA
R:
AGATACTGGGAGAGTGCAGAGC
Band lengths:
162-314
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)