HsaEX6070615 @ hg19
Exon Skipping
Gene
ENSG00000197616 | MYH6
Description
myosin, heavy chain 6, cardiac muscle, alpha [Source:HGNC Symbol;Acc:7576]
Coordinates
chr14:23862875-23865629:-
Coord C1 exon
chr14:23865493-23865629
Coord A exon
chr14:23863277-23863532
Coord C2 exon
chr14:23862875-23863117
Length
256 bp
Sequences
Splice sites
3' ss Seq
CCTCCACGTTTCCTTGCCAGGGA
3' ss Score
9.06
5' ss Seq
GCGGTGAGG
5' ss Score
7.93
Exon sequences
Seq C1 exon
GTGTTCTTCAAGGCAGGGCTGCTTGGGCTGCTGGAGGAGATGCGGGATGAGAGGCTGAGCCGCATCATCACGCGCATGCAGGCCCAAGCCCGGGGCCAGCTCATGCGCATTGAGTTCAAGAAGATAGTGGAACGCAG
Seq A exon
GGATGCCCTGCTGGTAATCCAGTGGAACATTCGGGCCTTCATGGGGGTCAAGAATTGGCCCTGGATGAAGCTCTACTTCAAGATCAAGCCGCTGCTGAAGAGCGCAGAGACGGAGAAGGAGATGGCCACCATGAAGGAAGAGTTCGGGCGCATCAAAGAGACGCTGGAGAAGTCCGAGGCTCGCCGCAAGGAGCTGGAGGAGAAGATGGTGTCCCTGCTGCAGGAGAAGAATGACCTGCAGCTCCAAGTGCAGGCG
Seq C2 exon
GAACAAGACAACCTCAATGATGCTGAGGAGCGCTGCGACCAGCTGATCAAAAACAAGATTCAGCTGGAGGCCAAAGTAAAGGAGATGAATGAGAGGCTGGAGGATGAGGAGGAGATGAACGCGGAGCTCACTGCCAAGAAGCGCAAGCTGGAAGACGAGTGCTCAGAGCTCAAGAAGGACATTGATGACCTGGAGCTGACACTGGCCAAGGTGGAGAAGGAGAAGCATGCAACAGAGAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197616-'19-21,'19-20,20-21=AN
Average complexity
A_S
Mappability confidence:
100%=100=75%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.070 C2=0.481
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PD(0.4=6.5)
A:
PF0157614=Myosin_tail_1=PU(27.0=61.6)
C2:
PF0157614=Myosin_tail_1=FE(40.8=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGAGATGCGGGATGAGAGG
R:
AGTGTCAGCTCCAGGTCATCA
Band lengths:
307-563
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)