HsaEX6070852 @ hg19
Exon Skipping
Gene
ENSG00000100448 | CTSG
Description
cathepsin G [Source:HGNC Symbol;Acc:2532]
Coordinates
chr14:25043451-25044618:-
Coord C1 exon
chr14:25044471-25044618
Coord A exon
chr14:25043881-25044016
Coord C2 exon
chr14:25043451-25043705
Length
136 bp
Sequences
Splice sites
3' ss Seq
CCTACCTCTTGCTTTTGCAGCAA
3' ss Score
10.5
5' ss Seq
CAGGTACCA
5' ss Score
7.88
Exon sequences
Seq C1 exon
GGGAGATCATCGGAGGCCGGGAGAGCAGGCCCCACTCCCGCCCCTACATGGCGTATCTTCAGATCCAGAGTCCAGCAGGTCAGAGCAGATGTGGAGGGTTCCTGGTGCGAGAAGACTTTGTGCTGACAGCAGCTCATTGCTGGGGAAG
Seq A exon
CAATATAAATGTCACCCTGGGCGCCCACAATATCCAGAGACGGGAAAACACCCAGCAACACATCACTGCGCGCAGAGCCATCCGCCACCCTCAATATAATCAGCGGACCATCCAGAATGACATCATGTTATTGCAG
Seq C2 exon
CTGAGCAGAAGAGTCAGACGGAATCGAAACGTGAACCCAGTGGCTCTGCCTAGAGCCCAGGAGGGACTGAGACCCGGGACGCTGTGCACTGTGGCCGGCTGGGGCAGGGTCAGCATGAGGAGGGGAACAGATACACTCCGAGAGGTGCAGCTGAGAGTGCAGAGGGATAGGCAGTGCCTCCGCATCTTCGGTTCCTACGACCCCCGAAGGCAGATTTGTGTGGGGGACCGGCGGGAACGGAAGGCTGCCTTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100448-'1-2,'1-1,2-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.240 A=0.435 C2=0.118
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(21.6=94.0)
A:
PF0008921=Trypsin=FE(20.6=100)
C2:
PF0008921=Trypsin=FE(38.5=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCAGGTCAGAGCAGATGTG
R:
GCCTATCCCTCTGCACTCTCA
Band lengths:
248-384
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)