HsaEX6075436 @ hg38
Exon Skipping
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65916828-65922472:-
Coord C1 exon
chr15:65922338-65922472
Coord A exon
chr15:65917966-65918094
Coord C2 exon
chr15:65916828-65916956
Length
129 bp
Sequences
Splice sites
3' ss Seq
AGGCTGCCCTGTGCCCACAGTGT
3' ss Score
7.62
5' ss Seq
AGGGTAAGC
5' ss Score
9.04
Exon sequences
Seq C1 exon
TCTGCCCCCCTGGGTTCTATGGCCACGGCTGCGCCCAGCCATGCCCCCTCTGCGTGCACAGCAGCAGGCCCTGCCACCACATCAGCGGCATCTGTGAGTGCCTCCCAGGATTCTCTGGAGCTCTCTGCAACCAAG
Seq A exon
TGTGTGCTGGAGGATACTTTGGGCAGGACTGTGCCCAGCTCTGCTCCTGTGCCAACAACGGGACCTGCAGCCCTATCGATGGCTCCTGCCAGTGCTTTCCTGGATGGATTGGCAAGGACTGCTCACAGG
Seq C2 exon
CTTGCCCACCCGGGTTCTGGGGCCCCGCCTGCTTCCACGCATGCAGCTGCCACAACGGGGCGAGCTGCAGCGCCGAGGACGGGGCCTGCCACTGCACCCCTGGCTGGACTGGACTCTTCTGCACACAGC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-'34-46,'34-45,38-46=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.002
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(29.2=30.4),PF126612=hEGF=WD(100=28.3)
A:
PF0005319=Laminin_EGF=PU(69.0=65.9)
C2:
PF0005319=Laminin_EGF=PD(28.6=27.3)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCCTGGGTTCTATGGCCA
R:
TGTGCAGAAGAGTCCAGTCCA
Band lengths:
254-383
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains