RnoEX6036176 @ rn6
Exon Skipping
Gene
ENSRNOG00000010634 | Megf11
Description
multiple EGF-like-domains 11 [Source:RGD Symbol;Acc:1582797]
Coordinates
chr8:70164489-70169590:+
Coord C1 exon
chr8:70164489-70164623
Coord A exon
chr8:70168233-70168361
Coord C2 exon
chr8:70169462-70169590
Length
129 bp
Sequences
Splice sites
3' ss Seq
AGGTTTCCCTGTGCCCACAGTGT
3' ss Score
8.14
5' ss Seq
AGGGTAAGC
5' ss Score
9.04
Exon sequences
Seq C1 exon
TCTGCCCACCAGGATTCTACGGCCATGGCTGCGCCCAGCCTTGTCCTCTCTGCGTGCACAGCAGGGGGCCCTGCCATCACGTCAGTGGCATTTGTGAGTGCCTGCCAGGATTCTCTGGAGCCTTGTGCAACCAAG
Seq A exon
TGTGTGCTGGAGGGCACTTTGGGCAGGACTGTGCCCAGCTCTGTTCCTGTGCCAACAACGGGACCTGCAGCCCCATTGATGGCTCCTGTCAATGCTTCCCTGGATGGACTGGCAAGGACTGCTCACAGG
Seq C2 exon
CCTGCCCATCTGGGTTCTGGGGCTCTGCCTGCTTCCACACATGCAGCTGCCACAACGGGGCGAGCTGCAGCGCCGAGGATGGGGCCTGCCACTGCACCCCTGGCTGGACCGGACTCTTCTGCACGCAGC
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000010634-'24-30,'24-29,25-30=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(33.3=37.0),PF126612=hEGF=WD(100=28.3)
A:
PF0005319=Laminin_EGF=PU(67.4=65.9)
C2:
PF0005319=Laminin_EGF=PD(30.2=29.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCAGGATTCTACGGCCATG
R:
TGCAGAAGAGTCCGGTCCAG
Band lengths:
252-381
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]