HsaEX6076318 @ hg38
Exon Skipping
Gene
ENSG00000181026 | AEN
Description
apoptosis enhancing nuclease [Source:HGNC Symbol;Acc:HGNC:25722]
Coordinates
chr15:88621296-88629426:+
Coord C1 exon
chr15:88621296-88621382
Coord A exon
chr15:88626146-88626749
Coord C2 exon
chr15:88629226-88629426
Length
604 bp
Sequences
Splice sites
3' ss Seq
CCTGTGTGTTCTCTCTTCAGGCT
3' ss Score
12.09
5' ss Seq
GAGGTAAGG
5' ss Score
10.28
Exon sequences
Seq C1 exon
AGTCGGAGCCGGGCTTGCCCGGGCATGTGGGAGCTGCCGGCTTTCCGGACGCCACGTGCAGACCGGAAGAGACACGCGGGGCTTCAG
Seq A exon
GCTGCTGCCCCATTGGAAGATTACTCCCCAGGCTTCCCTTGCCCCAAGCAGTGAGCTGACTGGAATGGTACCCCGGGAGGCCCCTGAGTCTGCTCAGTGCCTGTGCCCTTCCCTCACCATCCCAAATGCCAAGGATGTGCTTCGGAAGAGGCACAAGAGAAGGAGCCGACAGCACCAGCGGTTCATGGCCCGGAAGGCCTTGCTGCAGGAGCAGGGGCTGCTGAGCATGCCTCCAGAACCAGGGTCCTCCCCACTGCCCACCCCTTTCGGGGCAGCGACAGCAACTGAAGCTGCCAGCAGTGGGAAGCAGTGTCTGAGGGCTGGATCTGGCAGTGCCCCATGCAGCAGAAGGCCTGCTCCCGGGAAAGCCTCAGGGCCCTTGCCCAGCAAGTGTGTGGCTATCGACTGTGAGATGGTGGGCACGGGACCCCGAGGGCGGGTAAGCGAGCTGGCCCGCTGTTCCATTGTGAGCTACCATGGCAATGTCCTCTATGACAAGTACATCAGGCCTGAGATGCCCATCGCTGACTACCGTACCCGCTGGAGTGGCATCACTCGGCAGCACATGCGCAAGGCTGTCCCCTTCCAGGTGGCCCAGAAAGAG
Seq C2 exon
ATCCTTAAGCTCCTGAAGGGCAAGGTGGTGGTGGGGCACGCGCTGCACAACGACTTCCAGGCGCTCAAGTATGTCCACCCTCGGAGCCAGACCCGGGATACGACCTATGTCCCAAACTTCCTCAGCGAGCCCGGCCTCCACACCCGGGCCCGGGTCTCTCTAAAGGACCTGGCCCTGCAGCTGCTGCACAAGAAGATCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000181026-'0-3,'0-0,11-3
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.428 C2=0.075
Domain overlap (PFAM):
C1:
NA
A:
PF0092919=RNase_T=PU(44.2=38.3)
C2:
PF0092919=RNase_T=FE(42.3=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTTCCGGACGCCACGTG
R:
GGATCTTCTTGTGCAGCAGCT
Band lengths:
246-850
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains