HsaEX6083366 @ hg19
Exon Skipping
Gene
ENSG00000109758 | HGFAC
Description
HGF activator [Source:HGNC Symbol;Acc:4894]
Coordinates
chr4:3446992-3449358:+
Coord C1 exon
chr4:3446992-3447077
Coord A exon
chr4:3447769-3448021
Coord C2 exon
chr4:3449219-3449358
Length
253 bp
Sequences
Splice sites
3' ss Seq
CCGGTGACCTTTGCTCCCAGAAT
3' ss Score
7
5' ss Seq
CAGGTGCAC
5' ss Score
4.29
Exon sequences
Seq C1 exon
GAATCCGGACAATGACGAGAGGCCCTGGTGCTACGTGGTGAAGGACAGCGCGCTCTCCTGGGAGTACTGCCGCCTGGAGGCCTGCG
Seq A exon
AATCCCTCACCAGAGTCCAACTGTCACCGGATCTCCTGGCGACCCTGCCTGAGCCAGCCTCCCCGGGGCGCCAGGCCTGCGGCAGGAGGCACAAGAAGAGGACGTTCCTGCGGCCACGTATCATCGGCGGCTCCTCCTCGCTGCCCGGCTCGCACCCCTGGCTGGCCGCCATCTACATCGGGGACAGCTTCTGCGCCGGGAGCCTGGTCCACACCTGCTGGGTGGTGTCGGCCGCCCACTGCTTCTCCCACAG
Seq C2 exon
CCCCCCCAGGGACAGCGTCTCCGTGGTGCTGGGCCAGCACTTCTTCAACCGCACGACGGACGTGACGCAGACCTTCGGCATCGAGAAGTACATCCCGTACACCCTGTACTCGGTGTTCAACCCCAGCGACCACGACCTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109758-'8-12,'8-11,10-12=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.024 C2=0.000
Domain overlap (PFAM):
C1:
PF0005113=Kringle=PD(34.1=93.3)
A:
PF0008921=Trypsin=PU(18.8=51.8)
C2:
PF0008921=Trypsin=FE(20.1=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAATCCGGACAATGACGAGAGG
R:
CGTGGTCGCTGGGGTTGAA
Band lengths:
220-473
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)