HsaEX6087203 @ hg19
Exon Skipping
Gene
ENSG00000164344 | KLKB1
Description
kallikrein B, plasma (Fletcher factor) 1 [Source:HGNC Symbol;Acc:6371]
Coordinates
chr4:187172903-187175917:+
Coord C1 exon
chr4:187172903-187173015
Coord A exon
chr4:187173171-187173339
Coord C2 exon
chr4:187175742-187175917
Length
169 bp
Sequences
Splice sites
3' ss Seq
CGTCAACGCTCTCTTTTCAGTCT
3' ss Score
8.42
5' ss Seq
TGGGTAAGT
5' ss Score
10.24
Exon sequences
Seq C1 exon
GTGTAAGTGTTTCTTAAGATTATCTATGGATGGTTCTCCAACTAGGATTGCGTATGGGACACAAGGGAGCTCTGGTTACTCTTTGAGATTGTGTAACACTGGGGACAACTCTG
Seq A exon
TCTGCACAACAAAAACAAGCACACGCATTGTTGGAGGAACAAACTCTTCTTGGGGAGAGTGGCCCTGGCAGGTGAGCCTGCAGGTGAAGCTGACAGCTCAGAGGCACCTGTGTGGAGGGTCACTCATAGGACACCAGTGGGTCCTCACTGCTGCCCACTGCTTTGATGG
Seq C2 exon
GCTTCCCCTGCAGGATGTTTGGCGCATCTATAGTGGCATTTTAAATCTGTCAGACATTACAAAAGATACACCTTTCTCACAAATAAAAGAGATTATTATTCACCAAAACTATAAAGTCTCAGAAGGGAATCATGATATCGCCTTGATAAAACTCCAGGCTCCTTTGAATTACACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000164344-'17-21,'17-20,19-21=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0002421=PAN_1=PD(36.9=79.5)
A:
PF0008921=Trypsin=PU(20.3=82.5)
C2:
PF0008921=Trypsin=FE(25.5=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAACTAGGATTGCGTATGGGAC
R:
GTGTAATTCAAAGGAGCCTGGAGT
Band lengths:
250-419
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)