Special

HsaEX6089619 @ hg19

Exon Skipping

Gene
ENSG00000138115 | CYP2C8
Description
cytochrome P450, family 2, subfamily C, polypeptide 8 [Source:HGNC Symbol;Acc:2622]
Coordinates
chr10:96826965-96829254:-
Coord C1 exon
chr10:96828992-96829254
Coord A exon
chr10:96827286-96827448
Coord C2 exon
chr10:96826965-96827114
Length
163 bp
Sequences
Splice sites
3' ss Seq
ATTTGCATTTCCTTTCCCAGTTC
3' ss Score
9.18
5' ss Seq
TTGGTAGGT
5' ss Score
7.03
Exon sequences
Seq C1 exon
ACATGTCAAAGAGACACACACTAAATTAGCAGGGAGTGTTATAAAAACTTTGGAGTGCAAGCTCACAGCTGTCTTAATAAGAAGAGAAGGCTTCAATGGAACCTTTTGTGGTCCTGGTGCTGTGTCTCTCTTTTATGCTTCTCTTTTCACTCTGGAGACAGAGCTGTAGGAGAAGGAAGCTCCCTCCTGGCCCCACTCCTCTTCCTATTATTGGAAATATGCTACAGATAGATGTTAAGGACATCTGCAAATCTTTCACCAAT
Seq A exon
TTCTCAAAAGTCTATGGTCCTGTGTTCACCGTGTATTTTGGCATGAATCCCATAGTGGTGTTTCATGGATATGAGGCAGTGAAGGAAGCCCTGATTGATAATGGAGAGGAGTTTTCTGGAAGAGGCAATTCCCCAATATCTCAAAGAATTACTAAAGGACTTG
Seq C2 exon
GAATCATTTCCAGCAATGGAAAGAGATGGAAGGAGATCCGGCGTTTCTCCCTCACAACCTTGCGGAATTTTGGGATGGGGAAGAGGAGCATTGAGGACCGTGTTCAAGAGGAAGCTCACTGCCTTGTGGAGGAGTTGAGAAAAACCAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138115-'0-2,'0-1,2-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.018 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006717=p450=PU(5.7=46.4)

							
A:
PF0006717=p450=PD(23.1=75.0)

							
C2:
PF0006717=p450=PU(19.2=73.3)

						

					

				








    
Main Inclusion Isoform:
ENSP00000360317





     
                   









    
Main Skipping Isoform:
ENSP00000445062





     
      









    
Other Inclusion Isoforms:
ENSP00000433191, ENSP00000433314, ENSP00000442343
          









    
Other Skipping Isoforms:
ENSP00000433842
  



Associated events






Other assemblies


hg38




Conservation


Mouse
(mm10)
chr19:39643592-39643754 
Mouse
(mm9)
chr19:39718082-39718244 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr26:16376156-16376318 
Chicken
(galGal4)
chr3:108402643-108402805 
HIGH PSI
GgaEX0024687
([1])
Chicken
(galGal3)
chr6:17658584-17658746 
Zebrafish
(danRer10)
chr15:102397-102559 
HIGH PSI
DreEX6074626
(cyp2y3)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CTTTTGTGGTCCTGGTGCTGT

				
R: 
TTCCCCATCCCAAAATTCCGC

				
Band lengths: 
243-406

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Autistic and control brains






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