HsaEX6093545 @ hg38
Exon Skipping
Gene
ENSG00000074181 | NOTCH3
Description
notch 3 [Source:HGNC Symbol;Acc:HGNC:7883]
Coordinates
chr19:15180681-15181801:-
Coord C1 exon
chr19:15181576-15181801
Coord A exon
chr19:15180961-15181162
Coord C2 exon
chr19:15180681-15180828
Length
202 bp
Sequences
Splice sites
3' ss Seq
TCCCACTCCTTCCGCTCCAGCTC
3' ss Score
7.58
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
Exon sequences
Seq C1 exon
ACCCATGCCTGAACGGTGGCTCGTGCCAAGACGGCGTGGGCTCCTTTTCCTGCTCCTGCCTCCCTGGTTTCGCCGGCCCACGATGCGCCCGCGATGTGGATGAGTGCCTGAGCAACCCCTGCGGCCCGGGCACCTGTACCGACCACGTGGCCTCCTTCACCTGCACCTGCCCGCCAGGCTACGGAGGCTTCCACTGCGAACAGGACCTGCCCGACTGCAGCCCCAG
Seq A exon
CTCCTGCTTCAATGGCGGGACCTGTGTGGACGGCGTGAACTCGTTCAGCTGCCTGTGCCGTCCCGGCTACACAGGAGCCCACTGCCAACATGAGGCAGACCCCTGCCTCTCGCGGCCCTGCCTACACGGGGGCGTCTGCAGCGCCGCCCACCCTGGCTTCCGCTGCACCTGCCTCGAGAGCTTCACGGGCCCGCAGTGCCAG
Seq C2 exon
ACGCTGGTGGATTGGTGCAGCCGCCAGCCTTGTCAAAACGGGGGTCGCTGCGTCCAGACTGGGGCCTATTGCCTTTGTCCCCCTGGATGGAGCGGACGCCTCTGTGACATCCGAAGCTTGCCCTGCAGGGAGGCCGCAGCCCAGATCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000074181-'25-26,'25-24,26-26
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(0.1=0.0),PF0000822=EGF=PD(93.1=35.5),PF0764510=EGF_CA=WD(100=59.2),PF0000822=EGF=PU(9.7=3.9)
A:
PF0764510=EGF_CA=PD(0.1=0.0),PF0000822=EGF=PD(87.1=39.7),PF0000822=EGF=WD(100=45.6)
C2:
PF0000822=EGF=WD(100=58.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCTTTTCCTGCTCCTGCCTC
R:
GCAAGCTTCGGATGTCACAGA
Band lengths:
306-508
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains