HsaEX6101517 @ hg19
Exon Skipping
Gene
ENSG00000178187 | ZNF454
Description
zinc finger protein 454 [Source:HGNC Symbol;Acc:21200]
Coordinates
chr5:178369686-178373987:+
Coord C1 exon
chr5:178369686-178369825
Coord A exon
chr5:178373360-178373486
Coord C2 exon
chr5:178373898-178373987
Length
127 bp
Sequences
Splice sites
3' ss Seq
GAATGAATTTGCTGTTGCAGGAA
3' ss Score
7.41
5' ss Seq
TGGGTAAGT
5' ss Score
10.24
Exon sequences
Seq C1 exon
CAGGTGTGTGGACCCTTCTAGCCTGAGGAGTCCTGCAGGTGTGAAGCTCCACACCTGCCTCCATAGCACTTTGCCTGTCCCTAAGAGGGCTCATCGGAGAAGAAAGAATGGCTGTCAGCCACCTGCCAACCATGGTCCAG
Seq A exon
GAATCGGTGACCTTCAAGGATGTGGCTATACTGTTCACCCAGGAAGAGTGGGGGCAGCTGAGCCCCGCCCAGAGGGCCCTGTACAGGGACGTGATGCTGGAGAACTACAGCAACCTGGTCTCACTGG
Seq C2 exon
GACTCTTAGGACCCAAACCAGATACGTTTTCCCAGCTAGAAAAAAGGGAAGTGTGGATGCCAGAGGACACCCCTGGAGGCTTCTGTCTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000178187-'2-5,'2-4,4-5=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.161
Domain overlap (PFAM):
C1:
NO
A:
PF0135222=KRAB=WD(100=95.3)
C2:
PF0135222=KRAB=PD(0.1=0.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTGTGGACCCTTCTAGCCT
R:
AAGACAGAAGCCTCCAGGGG
Band lengths:
226-353
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)