HsaEX6101517 @ hg38
Exon Skipping
Gene
ENSG00000178187 | ZNF454
Description
zinc finger protein 454 [Source:HGNC Symbol;Acc:HGNC:21200]
Coordinates
chr5:178942685-178946986:+
Coord C1 exon
chr5:178942685-178942824
Coord A exon
chr5:178946359-178946485
Coord C2 exon
chr5:178946897-178946986
Length
127 bp
Sequences
Splice sites
3' ss Seq
GAATGAATTTGCTGTTGCAGGAA
3' ss Score
7.41
5' ss Seq
TGGGTAAGT
5' ss Score
10.24
Exon sequences
Seq C1 exon
CAGGTGTGTGGACCCTTCTAGCCTGAGGAGTCCTGCAGGTGTGAAGCTCCACACCTGCCTCCATAGCACTTTGCCTGTCCCTAAGAGGGCTCATCGGAGAAGAAAGAATGGCTGTCAGCCACCTGCCAACCATGGTCCAG
Seq A exon
GAATCGGTGACCTTCAAGGATGTGGCTATACTGTTCACCCAGGAAGAGTGGGGGCAGCTGAGCCCCGCCCAGAGGGCCCTGTACAGGGACGTGATGCTGGAGAACTACAGCAACCTGGTCTCACTGG
Seq C2 exon
GACTCTTAGGACCCAAACCAGATACGTTTTCCCAGCTAGAAAAAAGGGAAGTGTGGATGCCAGAGGACACCCCTGGAGGCTTCTGTCTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000178187-'3-6,'3-5,5-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.151
Domain overlap (PFAM):
C1:
NO
A:
PF0135222=KRAB=WD(100=95.3)
C2:
PF0135222=KRAB=PD(0.1=0.0)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGTGTGGACCCTTCTAGCCT
R:
AAGACAGAAGCCTCCAGGGG
Band lengths:
226-353
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains