HsaEX7000025 @ hg38
Exon Skipping
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3524124-3579929:-
Coord C1 exon
chr1:3579825-3579929
Coord A exon
chr1:3546998-3547123
Coord C2 exon
chr1:3524124-3524246
Length
126 bp
Sequences
Splice sites
3' ss Seq
ACCTGCTTCTCCCCTCGCAGATG
3' ss Score
12.28
5' ss Seq
AAGGTAGGG
5' ss Score
8.76
Exon sequences
Seq C1 exon
CTGAATGCAGCGCCAGCCTCTGTTTTCACGGTGGCCGTTGTGTGCCAGGCTCAGCCCAGCCGTGTCACTGTCCCCCCGGCTTCCAGGGACCCCGCTGTCAGTATG
Seq A exon
ATGTGGGTGAGTGTGCCAACGCCAACGGGGGCTGTGCGGGTCGGTGCCGGGACACCGTGGGGGGCTTCTACTGCCGCTGGCCCCCCCCCAGCCACCAGCTGCAGGGTGATGGCGAGACTTGCCAAG
Seq C2 exon
ATGTGGACGAATGCCGAACCCACAACGGTGGCTGCCAGCACCGGTGCGTGAACACCCCAGGCTCCTACCTCTGTGAGTGCAAGCCCGGCTTCCGGCTCCACACTGACAGCAGGACCTGCCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591-'10-17,'10-10,11-17=AN
Average complexity
A_C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.045 A=0.000 C2=0.062
Domain overlap (PFAM):
C1:
PF079748=EGF_2=WD(100=86.1)
A:
PF146701=FXa_inhibition=WD(100=86.0)
C2:
PF146701=FXa_inhibition=WD(100=85.7)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAATGCAGCGCCAGCCTC
R:
CAGGTCCTGCTGTCAGTGTG
Band lengths:
221-347
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains