HsaEX7103518 @ hg38
Exon Skipping
Gene
ENSG00000133256 | PDE6B
Description
phosphodiesterase 6B [Source:HGNC Symbol;Acc:HGNC:8786]
Coordinates
chr4:635880-653992:+
Coord C1 exon
chr4:635880-635969
Coord A exon
chr4:652496-652553
Coord C2 exon
chr4:653852-653992
Length
58 bp
Sequences
Splice sites
3' ss Seq
CTGGAGCTGTGGGCTTCAAGGTC
3' ss Score
2.37
5' ss Seq
TCGGTAAGT
5' ss Score
11.78
Exon sequences
Seq C1 exon
GTGTTCTTGAAGTACCTGAATTTTGCCACGTTGTACCTGAAGATCTATCACCTGAGCTACCTCCACAACTGCGAGACGCGCCGCGGCCAG
Seq A exon
GTCAGCCGCGCTGTGTGGCGGCCACCACTGCCGTTAACCACAGTACACAGGGTGCTCG
Seq C2 exon
GTGCTGCTGTGGTCGGCCAACAAGGTGTTTGAGGAGCTGACGGACATCGAGAGGCAGTTCCACAAGGCCTTCTACACGGTGCGGGCCTACCTCAACTGCGAGCGGTACTCCGTGGGCCTCCTGGACATGACCAAGGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133256-'8-17,'8-12,11-17=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=0.017 A=0.000 C2=0.112
Domain overlap (PFAM):
C1:
PF0159021=GAF=PD(7.4=36.7)
A:
NA
C2:
PF0159021=GAF=PU(18.0=68.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGAGCTACCTCCACAACTGC
R:
TACCGCTCGCAGTTGAGGTAG
Band lengths:
146-204
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains