HsaEX7104387 @ hg38
Exon Skipping
Gene
ENSG00000241404 | EGFL8
Description
EGF like domain multiple 8 [Source:HGNC Symbol;Acc:HGNC:13944]
Coordinates
chr6:32167087-32167656:+
Coord C1 exon
chr6:32167087-32167257
Coord A exon
chr6:32167350-32167429
Coord C2 exon
chr6:32167503-32167656
Length
80 bp
Sequences
Splice sites
3' ss Seq
TTGGTCTCCTTTGTCCCTAGTTC
3' ss Score
9.48
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
ACGTGGATGAATGTAGGACCAGCATCACCCTCTGCTCGCACCATTGTTTTAATACGGCAGGCAGCTTCACCTGCGGCTGCCCCCATGACCTAGTGCTAGGCGTGGACGGGCGCACCTGCATGGAGGGGTCCCCAGAGCCCCCAACCAGTGCCAGCATACTCAGCGTGGCCG
Seq A exon
TTCGGGAGGCGGAAAAAGATGAGCGCGCTCTGAAGCAGGAGATTCACGAGCTGCGAGGGCGCCTGGAGCGGCTGGAGCAG
Seq C2 exon
TGGGCCGGTCAGGCTGGGGCCTGGGTCAGAGCGGTGCTGCCCGTGCCGCCTGAAGAGCTGCAGCCAGAACAGGTGGCTGAGCTGTGGGGCCGGGGTGACCGGATCGAATCTCTCAGCGACCAGGTGCTGCTGCTGGAGGAGAGGCTAGGTGCCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000241404-'8-10,'8-9,9-10=AN
Average complexity
A_NA
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.130 A=0.000 C2=0.090
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=69.0)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAACCAGTGCCAGCATACTC
R:
CCTAGCCTCTCCTCCAGCAG
Band lengths:
180-260
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains