HsaINT0000055 @ hg38
Intron Retention
Gene
ENSG00000175899 | A2M
Description
alpha-2-macroglobulin [Source:HGNC Symbol;Acc:HGNC:7]
Coordinates
chr12:9107524-9109405:-
Coord C1 exon
chr12:9109321-9109405
Coord A exon
chr12:9107645-9109320
Coord C2 exon
chr12:9107524-9107644
Length
1676 bp
Sequences
Splice sites
5' ss Seq
CCTGTGAGT
5' ss Score
7.21
3' ss Seq
TGGGAATGTTCTCATGACAGATA
3' ss Score
5.98
Exon sequences
Seq C1 exon
TTCTTCCCAAGTTTGAAGTACAAGTAACAGTGCCAAAGATAATCACCATCTTGGAAGAAGAGATGAATGTATCAGTGTGTGGCCT
Seq A exon
GTGAGTTCATTTTTTAAAAATCTTTTGTGGGGGATTATTTAAAAGAGACTCACCATTTGGGATATTTTAACTACTCTCTCCGGGAGCAGTGGCAACACAAAAATTTTAAGTGCTTTGACAGCATCCTCATCTGTAGAATGTTATTCTCCTGTTGCTTTTCTATTTTTATTTTCTTTCACGTTCTTATCAGTATTATTCTATCATGAGGTAAGAAACTGTTTCTAGAGAGGTTATGCTAATAGGATTGATTCTGAAAGTGACAAAACTGCACACACACACACACACAAAATGGGAAGGGTGGATAGTGTTGAAGGGTATTGGTTCTGCCTTAACCAAAAATAACCAAACGTATATTAGGGAGATAATTAACACATGGCTATAGGGGAAATTCAATCATCAACAGATCATTTACCTGACCTTGCATGCTTACTGGAAAAATCACTTAGATTCAGAATTTGTAGAGATAGGCATACAACTGAAATCTCATCTAACTCACTAGTCCACCTAAGGCGGGTCTACATACCTGTCTGCACTGACATTTTTACGAAGAGACTGAACGTGATTTCTCAAGACAGTCTGTTCCAACCTTGAAAAGTCTTGTTTCCTGGATCTTATGTTCCCATCCATGGTGGCACACAGTAGCAGTAGCAGGAAGAGCAGGTATAGTCCTGTCCAAAGATCACACATGTAATACACCTACTATTCAGCTAGGCCCCTGCTCCAGTTCTGTCTCACAGTGATGGCCAAGTTCCTGGTTCCTCATAACTGGTGTGATCTTGCAAATAGACATACAGAGGACATTCTCAAATAGGAAAGGAGACAAATGCACTTGGAAACCCAGCAATTGTCTATGACATATTTACGACACAATCCCACTTTTGTAAAAAAGTAAACAGGCCCGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACGAGGTCAGGAGATCAAGACCATCCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAAAATACAAAAAATTAGCCAGGCATGGTGGCCAGCGCCTGTAGTCCCAGCTACTTGGGAAGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGTGGAGGTTGCAGTGAGCCAAGATCGCACCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAAATAAACAAGTGAAACTCGATATAGAGATGGCTGCACATGGGGAGAGGATGATGGAAGAAGAGACACTATCGTACTAATAGTTTGTATTCCTAGGTAGACTTGAGGGCGTTTGGGTTTTTTTTGTTCTGTTTTGTTTTGTTTGTTTCGTCTTGCTGGTATTGTTTCTCTTTTAAGAACGGGTTTAAGTTTTATAATAAGAAAGACTTTTTTAAGATAAAACTAAAAAAAAACGAGGAAAAAAAAGAAATGATAAAAGAAGAATGTAAATTTCAGCATGTTGCAATGGAGATTTCTATAAGAGCCATTAGTGACTCTTGTCTTCAATATTGTGTGAGCCCAGCAGAGAGCAGAGGGAAGTACAGACAGGGAATATACTGTAGCTAAAGGGGAGATATAAATAGCTAGAAAATGGGGAGGTTCAGTGTCTGCTCTGATTCCTTTGGGAATGTTCTCATGACAG
Seq C2 exon
ATACACATATGGGAAGCCTGTCCCTGGACATGTGACTGTGAGCATTTGCAGAAAGTATAGTGACGCTTCCGACTGCCACGGTGAAGATTCACAGGCTTTCTGTGAGAAATTCAGTGGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175899:ENST00000318602:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCTTCCCAAGTTTGAAGTACAAGT
R:
CTGTCCACTGAATTTCTCACAGA
Band lengths:
206-1882
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development