HsaINT0000061 @ hg38
Intron Retention
Gene
ENSG00000166535 | A2ML1
Description
alpha-2-macroglobulin like 1 [Source:HGNC Symbol;Acc:HGNC:23336]
Coordinates
chr12:8843134-8845502:+
Coord C1 exon
chr12:8843134-8843361
Coord A exon
chr12:8843362-8845441
Coord C2 exon
chr12:8845442-8845502
Length
2080 bp
Sequences
Splice sites
5' ss Seq
TATGTGAGA
5' ss Score
1.04
3' ss Seq
TCTTTTCTTTTCTTCTTTAGTTA
3' ss Score
10.03
Exon sequences
Seq C1 exon
GGAAAGTTTCAAATGGAAGACTTAGTATATAATCCGGAACAAGTGCCACGTTACTACCAAAATGCCTACCTGCACCTGCGACCCTTCTACAGCACAACCCGCAGCTTCCTTGGCATCCACCGGCTAAACGGCCCCTTGAAATGTGGCCAGCCCCAGGAAGTGCTGGTGGATTATTACATCGACCCGGCCGATGCAAGCCCTGACCAAGAGATCAGCTTCTCCTACTAT
Seq A exon
GTGAGACCGGGAAACGGGGACGGGTGAGAGTATGCTGGGAAGGAAAGAGAATGAGAAGAGTCAGCCAGAGGGTGCACCTAGGCTATCTGAATTGCAGATGCACATCTAATTAAAAACAATTTTAAAGCCACACTAAAAAAGTAAAAGAACAGTTGACATTAATTTTAAATGTATTTTTTATTTAACCCATTATATCCAAAATATTAACATTTTAACACGAAAGCCATATAAAAAGTTTTAATAGATATTTTACATTCTTGTTTCAACGGTGTCTTTGAAACTCAGTATGTATTTTACACTTAAAGCGTATCTCAGTTTGGACTGAGCACATTTCAAGTATTCAATATTCCTTTTTTTTTCTTTTTTTTTTTTTTTGAGACACAGTCTCGCTCAGTTGCCCAGGCTGGAGTGCAGTGGTGTGTTCTTGGCTCACTGCAAGCTCCACCTCCCAGGTTCACGCCATTCTCCTGTCTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCCAGCTAATTTTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAACTAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCTGCCTCAGTCTCCCAGAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCTCAAGTATTCAATATTCCTATGTGGCTATGAGATACTGCATGGCCCAGTATAGGTGTAAGAGATGGAAAACATTGGGGGAAGAAAGAGATTCTGAGCAGGAACACAGGAAAATTGTGTGGGAAAATAAAATGAGGAATTACCTGAGAAAATAGTGCTGGCCAGGACCAAAAAAAACAAAAACAAAAACAAAACCAGCTGGGTGGTTGGGAGGGAGAGTGGGGAGGGATGGGACTCAGGATACTTTTTTTTTTTTTTTAATTTATATGAGACAGGGTTTCGCCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGACTGCAGGCATGAGCCACCGAGCCCAGCCAGGATACATTTCATTCTGTGTTCCATTGGTCAATATTATCAAATAGATGATATGGGGTTAAATTCACATCGATAGCAGCCTCATTGGGGAAATAAAATCATAACTTGGTAGCCTGAAAGCAATGTATAAGGATAAGCAGCTTTCCTGTCACCTTGGTGACAGTCAGGAAGTAGAATGGAAACCTCAGGTTTGATGGCTCGGAGCCTCTTTGTTCCGTTATCCTCCTGTCAGTCTATGAGAGACTTTCTCCCCTCTGGATCATTGCAGTAGCTTCCATGGTTTCAGTGTTGTCGTTAAGTGAAAAAAAAAAAATCATCCTAATACAACGAAAAGAGAAAAGATAGGTGGAAAATAACAAGTCCAGTGATAAAGCGGGCTCTGTCTTCAGGACCGAAGTGTGGGGAGGTGTAGGACAAAAGTGAAGTTAGGGCCGAGCCACGTGGAATGGCTAATGCTGGGCAGGCGTCCAAGGAACCGACCTTGGAGCCCTGCAGGAGCGTGGGATGAGAGCCTGCTTGCAAACAAGATCACCGAGTTCTGTTTCAAGTGAGAGTGGACGGGAAGGGGGAGTTAGAAGAGGAGATTTCTCCTCTAGAGGGTTCAATGTCAGAAGGGCTCAGGGTGGTTTAGGATGAAATTATTTCCACTGAATTTTAAATTGAGCTGTAATTAAAAAACACTTATGAGGATAGATTTTCGCTGACTTTCTGTTACAAAGATTATAAGAAAATAAAATTTGGAGATCTTCAAGAAATGGCAGACAGTTATCTATGGTGAGGAACAATTTCTATGCTGTCAGACTCCTCCCATCCACCTGCGTGGTTCTCAGCCAGACCTCCAACTGCAGGAGGAGCCACCAGGACCCGTTGGCAGCATCCTGCATTTGTCAAGCTAGTGGATGCTGGGTGAGGTATTGACCCGGACTCTGAACTGTGAAAGGAACCTCTCCTCATGAAGGGATGCAGAGATGCTCTGGAAGTTGGTCCAAGGTGAAATTACTGTAACTTCTGTGCAGTTGATTCTTTTCTTTTCTTCTTTAG
Seq C2 exon
TTAATAGGGAAAGGAAGTTTGGTGATGGAGGGGCAGAAACACCTGAACTCTAAGAAGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166535:ENST00000299698:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF077039=A2M_N_2=PU(26.2=51.3)
A:
NA
C2:
PF077039=A2M_N_2=FE(13.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development