HsaINT0000085 @ hg38
Intron Retention
Gene
ENSG00000166535 | A2ML1
Description
alpha-2-macroglobulin like 1 [Source:HGNC Symbol;Acc:HGNC:23336]
Coordinates
chr12:8874425-8875012:+
Coord C1 exon
chr12:8874425-8874527
Coord A exon
chr12:8874528-8874970
Coord C2 exon
chr12:8874971-8875012
Length
443 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
3' ss Seq
TGACTTATTTCATTTCACAGATG
3' ss Score
9.9
Exon sequences
Seq C1 exon
CTCATTAAGAACACTCAGACTTACACCTTCACCATCAGCCAAAGTGTGCTGGTCACCAACTTGAAACCAGCAACCATCAAGGTCTATGACTACTACCTACCAG
Seq A exon
GTGAGAGGGCTGAGCTGAAATGAGATCTGAGATCTTACCTGCATCTCCCAACTTACTTCTGCCTCATTCTTCATGGCTTCTCTCTTAATTTTACAAATACTCCTTCCCAAGCCAAGTAGCACATAATTAAATTATCTAATCTCCTAAAATATTTTAATTCAGTTGTGTGCCATTTTTAAGTTGCGTACACTAGAGACATTTTATGTGATCGGAGAACAATGTGAACCATTGTTCTCAAAGGGCTATTTCTATTATTTTTGGTATGATTAATAGTTTGTCACAATGTACAAATATTAGTGATTGAAACTTTCTTGTAATTCTGAATATGCTCATAACCTGTAGAGATTCTCTGGAAGGGGCTCAAGCAGTAGCTTTTCTGAAGCATTTTCCCTCTGAATATAGGAGGCCCTCAAAGTAATAATATGACTTATTTCATTTCACAG
Seq C2 exon
ATGAACAGGCAACAATTCAGTATTCTGATCCCTGTGAATGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166535:ENST00000299698:34
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.076
Domain overlap (PFAM):
C1:
PF076779=A2M_recep=FE(38.6=100)
A:
NA
C2:
PF076779=A2M_recep=PD(8.0=50.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development