HsaINT0000372 @ hg19
Intron Retention
Gene
ENSG00000165029 | ABCA1
Description
ATP-binding cassette, sub-family A (ABC1), member 1 [Source:HGNC Symbol;Acc:29]
Coordinates
chr9:107584777-107586859:-
Coord C1 exon
chr9:107586746-107586859
Coord A exon
chr9:107584949-107586745
Coord C2 exon
chr9:107584777-107584948
Length
1797 bp
Sequences
Splice sites
5' ss Seq
AAAGTAAGT
5' ss Score
9.72
3' ss Seq
TGTCTTCTCTCCTGTCACAGTCT
3' ss Score
9.36
Exon sequences
Seq C1 exon
GCCAGTACGGAATTCCCAGGCCCTGGTATTTTCCTTGCACCAAGTCCTACTGGTTTGGCGAGGAAAGTGATGAGAAGAGCCACCCTGGTTCCAACCAGAAGAGAATATCAGAAA
Seq A exon
GTAAGTGCTGTTGACCTCCTGCTCTTTCTTTAACCTAGTGCTGCTGCCTCTGCTAACTGTTGGGGGCAAGCGATGTCTCCTGCCTTTCTAAAAGACTGTGAAACCACTCCAGGGGCAGAGAAATCACATGCAGTGTCCCTTTCCAAATCCTCCCATGCCATTTATGTCCAATGCTGTTGACCTATTGGGAGTTCACGGTCTCGATCCCTGAGGGACATTTTCTTTGTTGTCTTGGCTTCTAGAAGAGTATCTTTTACTTGCCCCCTCCCAAACACACATTTCATGGTCTCCTAACAAGCTAGAAGAAAGAGGTAAAGACAAGCGTGATTGTGGAACCATAGCCTCGCTGCCTGCCTGTGACATGGTGACCTGTGTATCAGCCTGTGTGGGCTGAGACCAAGTGGCTACCACAGAGCTCAGCCTATGCTTCATAATGTAATCATTACCCAGATCCCTAATCCTCTCTTGGCTCTTAACTGCAGACAGAGATGTCCACAGCTCATCAAAGGCTCTGCCTTCTGGGTTCTTTGTGCTTAGAGTGGCTTCCTAAATATTTAATAGGTCCCTTTTCTGCCAGTCTCTTCTGTGCCCATCCCCTGATTGCCCTTGGTAAAAGTATGATGCCCCTTAGTGTAGCACGCTTGCCTGCTGTTCCTAATCATCTTCTCCTACCTCCTCTTTACACCTAGCTCCTGTTTCAGTCACCTAGAAATGCTCACAGTCGCTGGAATATGTCATGTTCTTCCACACCTCCATGCCTTTGTAGGTACTGTTTGCTCTCACAGGAGAACTTTCTCTCTAACTTGCCTATCTTCTCAACTCCTCCTTTCTCTCCAAGATCTAGTTCCGGATCCCCTCCCCTGAGCATCCCTCCTTGGTTCTCAGGTAGTCAGTCACTCTCTGCCCTGAACTTCCATGGCACGTGAAAGAAAATCTTTTTATTTTAAAACAATTACAGACTCACAAGAAGTAATACAAATTACATGAGGGGGTTCCCTTAAACCTTTCATCCAGTTTCCCCAATGGTAGCAGCATGTGTAACTGTAGAATAGTATCAAAACCATGAAATTGACATAGGTACAATTCACAAACCTTCTTCAGATTTCACTAGCTTTATGTGCGCTCATTTGTGTGTGTGTGTGCGTATTTAGTTCTATGCAATTTTATCATGTGTGAATTCATGTAATTACTAGCTCAGTCAAGCTGCAGAAATATCTCATTGTCACAAAGCTCCTTCATGCTACCCCTTAATGGCCACAGCCACCTCCCTTCTTCCTCAGTTCCTGACACCTGTCAACCACTAATGCGTTCCTCGTTTTTACAGTTTTATTATTTCTAGAATGTTACATAAATGGAACCATACAGTAGGTATCCTTTTGATACTGGCTTTTTTTTTTTTTCACTCAGCAGTATTCCCTTAGATCTATCCAAGTTGTGTGTGTCAACAGTTCATTCCTCTTCACTGCTGAGTAGTGTTCCCTGGGAGGGGTGTATCACAGTTCCATGGCATTTTTAGATGTATTTTTTAAACAGCTTTCAGCATCCTCTATTTTAATTGTTCATCAAGTCCTTTTTCCCAATAGACTCTGAATGCTCCTTTATCATCGTATTCCCATCACCAACATCAGTACCCAAATAGGCCCTAAATAAACATTTATAGCCTCCTGCCTGCCTGAGAAACCAGGGTGGACATGGAGAGAAGGCACTTCTGAAAGTTCAAGCGCAGTGCCCTGTGTCCTTACACTCCACTCCTCAGTGCTTTCTGTGGGTTCATTTCTGTCTTCTCTCCTGTCACAG
Seq C2 exon
TCTGCATGGAGGAGGAACCCACCCACTTGAAGCTGGGCGTGTCCATTCAGAACCTGGTAAAAGTCTACCGAGATGGGATGAAGGTGGCTGTCGATGGCCTGGCACTGAATTTTTATGAGGGCCAGATCACCTCCTTCCTGGGCCACAATGGAGCGGGGAAGACGACCACCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000165029-ABCA1:NM_005502:18
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.256 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0000522=ABC_tran=PU(18.5=46.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCAGTACGGAATTCCCAGG
R:
ATGGTGGTCGTCTTCCCCG
Band lengths:
286-2083
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)